UniProt P15559
NAD(P)H dehydrogenase [quinone] 1 (P15559)
NAD(P)H dehydrogenase [quinone] 1 (UniProt P15559): 35 experimental structures on GenesisL1, 8 ligands bound, 8 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P15559
- Protein
- NAD(P)H dehydrogenase [quinone] 1
- Experimental structures
- 35
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 8 · 1 record with a druggable one
Structures
35 records of P15559 in the MolNFT archive: 35 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1D4A | Crystal structure of human NAD[P]H-quinone oxidoreductase at 1.7 a resolution | x-ray diffraction | A, B, C, D | — | — |
| 1D4A | Crystal structure of human NAD[P]H-quinone oxidoreductase at 1.7 a resolution | x-ray diffraction | A, B, C, D | — | — |
| 1DXO | Crystal structure of human NAD[P]H-QUINONE oxidoreductase CO with 2,3,5,6,tetramethyl-P-benzoqui… | x-ray diffraction | A, B, C, D | — | — |
| 1DXO | Crystal structure of human NAD[P]H-quinone oxidoreductase co with 2,3… | x-ray diffraction | A, B, C, D | — | — |
| 1GG5 | Crystal structure of a complex of human NAD[P]H-quinone oxidoreductase and a chemotherapeutic drug… | x-ray diffraction | A, B, C, D | — | — |
| 1GG5 | Crystal structure of a complex of human NAD[P]H-quinone oxidoreductase and a chemotherapeutic drug… | x-ray diffraction | A, B, C, D | — | — |
| 1H66 | CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE CO WITH… | x-ray diffraction | A, B, C, D | — | — |
| 1H66 | Crystal structure of human NAD[P]H-quinone oxidoreductase co with… | x-ray diffraction | A, B, C, D | — | — |
| 1H69 | Crystal structure of human NAD[P]H-quinone oxidoreductase co with… | x-ray diffraction | A, B, C, D | — | — |
| 1H69 | Crystal structure of human NAD[P]H-quinone oxidoreductase co with… | x-ray diffraction | A, B, C, D | — | — |
| 1KBO | Complex of Human recombinant NAD(P)H:Qui Oxide reductase type 1 with… | x-ray diffraction | A, B, C, D | — | — |
| 1KBO | Complex of human recombinant NAD(P)H:QUINONE oxide reductase type 1 with 5-methoxy-1,2-dimethyl-3… | x-ray diffraction | A, B, C, D | — | — |
| 1KBQ | Complex of Human NAD(P)H qui Oxidoreductase with 5-methoxy-1,2-dimethyl-3-(4-nitrophenoxymethyl)indo… | x-ray diffraction | A, B, C, D | — | — |
| 1KBQ | Complex of human NAD(P)H quinone oxidoreductase with 5… | x-ray diffraction | A, B, C, D | — | — |
| 1QBG | Crystal structure of human dt-diaphorase (NAD(P)H oxidoreductase) | x-ray diffraction | A, B, C, D | — | — |
| 1QBG | Crystal structure of human dt-diaphorase (NAD(P)H oxidoreductase) | x-ray diffraction | A, B, C, D | — | — |
| 2F1O | Crystal Structure of NQO1 with Dicoumarol | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 2F1O | Crystal structure of NQO1 with dicoumarol | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3JSX | X-ray Crystal structure of NAD(P)H: Qui Oxidoreductase-1 (NQO1) bound to the coumarin-based… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3JSX | X-ray crystal structure of NAD(P)H: quinone oxidoreductase-1 (NQO1) bound to the coumarin-based… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4CET | Crystal structure of the complex of the P187S variant of human NAD(P) H:qui oxidoreductase with… | x-ray diffraction | A | — | — |
| 4CET | Crystal structure of the complex of the P187S variant of human NAD(P)H:QUINONE oxidoreductase with… | x-ray diffraction | A | — | — |
| 4CF6 | Crystal structure of the complex of the P187S variant of human NAD(P) H:qui oxidoreductase with… | x-ray diffraction | A, B | — | — |
| 4CF6 | Crystal structure of the complex of the P187S variant of human NAD(P) H:QUINONE oxidoreductase with… | x-ray diffraction | A, B | — | — |
| 5A4K | Crystal structure of the R139W variant of human NAD(P)H:QUINONE oxidoreductase | x-ray diffraction | A, B, C, D | — | — |
| 5EA2 | Crystal Structure of Holo NAD(P)H dehydrogenase, qui 1 | x-ray diffraction | A, C, E, G | FAD | — |
| 5EA2 | Crystal structure of holo NAD(P)H dehydrogenase, quinone 1 | x-ray diffraction | A, C, E, G | — | — |
| 5EAI | Crystal Structure of NAD(P)H dehydrogenase, qui 1 complexed with a chemotherapeutic naphthoqui E6a | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | FAD, E6A | — |
| 5EAI | Crystal structure of NAD(P)H dehydrogenase, quinone 1 complexed with a chemotherapeutic… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 5FUQ | Crystal structure of the H80R variant of NQO1 bound to dicoumarol | x-ray diffraction | A, B | FAD, DTC | — |
| 5FUQ | Crystal structure of the H80R variant of NQO1 bound to dicoumarol | x-ray diffraction | A, B | — | — |
| 6FY4 | Structure of human NAD(P) H:QUINONE oxidoreductase in complex with N… | x-ray diffraction | A, B, C, D | FAD, EAW | — |
| 6LLC | Discovery of a dual inhibitor of NQO1 and GSTP1 for treating malignant glioblastoma | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | FAD, EHL, SO4 | — |
| 8OK0 | Crystal structure of human NQO1 in complex with the inhibitor PMSF | x-ray diffraction | A, D, B, C | FAD, PMS, ACE | 8 (best 0.84) |
| P15559 | AlphaFold monomer V2.0 prediction for NAD(P)H dehydrogenase [quinone] 1 (P15559) | — | — | — |
Ligands
- FAD · Flavin-adenine dinucleotide · in 6 records
- ACE · Acetyl group · in 1 record
- DTC · Bishydroxy[2h-1-benzopyran-2-one,1,2-benzopyrone] · in 1 record
- E6A · (2~{R},3~{R})-2-[(2~{S},3~{S})-3-bromanyl-1,4-bis(oxidanylidene)-2,3-dihydronaphthalen-2-yl]-3-oxidanyl-2,3-dihydronaphthalene-1,4-dione · in 1 record
- EAW · N-(2-bromophenyl)pyrrolidine-1-sulfonamide · in 1 record
- EHL · 5-methyl-N-(5-nitro-1,3-thiazol-2-yl)-3-phenyl-1,2-oxazole-4-carboxamide · in 1 record
- PMS · phenylmethanesulfonic acid · in 1 record
- SO4 · Sulfate ion · in 1 record
Elsewhere
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