UniProt P15498
Proto-oncogene vav (P15498)
Proto-oncogene vav (UniProt P15498): 18 experimental structures on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P15498
- Protein
- Proto-oncogene vav
- Experimental structures
- 18
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 3 · 1 record with a druggable one
Structures
18 records of P15498 in the MolNFT archive: 18 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2CRH | Solution structure of the SH2 domain of human proto-oncogene protein VAV1 | solution nmr | A | — | — |
| 2CRH | Solution structure of the SH2 domain of human proto-oncogene protein VAV1 | solution nmr | A | — | — |
| 2LCT | Solution structure of the Vav1 SH2 domain complexed with a Syk-derived doubly phosphorylated peptide | solution nmr | A | — | — |
| 2LCT | Solution structure of the VAV1 SH2 domain complexed with a syk-derived doubly phosphorylated peptide | solution nmr | A | — | — |
| 2MC1 | Solution structure of the Vav1 SH2 domain complexed with a Syk-derived singly phosphorylated peptide | solution nmr | A | — | — |
| 2MC1 | Solution structure of the VAV1 SH2 domain complexed with a syk-derived singly phosphorylated peptide | solution nmr | A | — | — |
| 2ROR | Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from… | solution nmr | A | — | — |
| 2ROR | Solution structure of the VAV1 SH2 domain complexed with a tyrosine- phosphorylated peptide from… | solution nmr | A | — | — |
| 3BJI | Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1 | x-ray diffraction | A, B | — | — |
| 3BJI | Structural basis of promiscuous guanine nucleotide exchange by the T-cell essential VAV1 | x-ray diffraction | A, B | — | — |
| 3KY9 | Autoinhibited Vav1 | x-ray diffraction | A, B | — | — |
| 3KY9 | Autoinhibited VAV1 | x-ray diffraction | A, B | — | — |
| 6NEW | Apo structure of the activated truncation of Vav1 | x-ray diffraction | A | ZN | 3 (best 0.59) |
| 6NEW | Apo structure of the activated truncation of VAV1 | x-ray diffraction | A | ZN | — |
| 6NF1 | Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity | x-ray diffraction | A | 9JY, ZN | — |
| 6NF1 | VAV1 inhibited by an allosteric inhibitor: VAV1 inhibitors block gef activity | x-ray diffraction | A | 9JY, ZN | — |
| 6NFA | VAV1 inhibited by an allosteric inhibitor: VAV1 inhibitors block gef activity | x-ray diffraction | A | ZN, 9K1 | — |
| P15498 | AlphaFold monomer V2.0 prediction for proto-oncogene vav (P15498) | — | — | — |
Ligands
Elsewhere
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