UniProt P15328
P15328
P15328 (UniProt P15328): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P15328
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
Structures
11 records of P15328 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4KM6 | Human folate receptor alpha (FOLR1) at acidic pH, orthorhombic form | x-ray diffraction | A | — | — |
| 4KM6 | Human folate receptor alpha (FOLR1) at acidic pH, orthorhombic form | x-ray diffraction | A | — | — |
| 4KM7 | Human folate receptor alpha (FOLR1) at acidic pH, triclinic form | x-ray diffraction | A, B | — | — |
| 4KM7 | Human folate receptor alpha (FOLR1) at acidic pH, triclinic form | x-ray diffraction | A, B | — | — |
| 4KMX | Human folate receptor alpha (FOLR1) at acidic pH, hexagonal form | x-ray diffraction | A | — | — |
| 4KMX | Human folate receptor alpha (FOLR1) at acidic pH, hexagonal form | x-ray diffraction | A | — | — |
| 4LRH | Crystal structure of human folate receptor alpha in complex with folic acid | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4LRH | Crystal structure of human folate receptor alpha in complex with folic acid | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 5IZQ | Crystal structure of human folate receptor alpha in complex with novel antifolate AGF183 | x-ray diffraction | A, B, C, D, E, F, G, H | 83A | — |
| 5IZQ | Crystal structure of human folate receptor alpha in complex with novel antifolate AGF183 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| P15328 | AlphaFold monomer V2.0 prediction for folate receptor alpha (P15328) | predicted | A | — | — |
Ligands
- 83A · N-(4-{[2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)ethyl]amino}benzene-1-carbonyl)-L-glutamic acid · in 1 record
Experiment against prediction
- 5IZQ chain B against the predicted model P15328: TM-score 0.98, RMSD 0.74 Å
- 5IZQ chain B against the predicted model P15328: TM-score 0.98, RMSD 0.74 Å
- 5IZQ chain H against the predicted model P15328: TM-score 0.98, RMSD 0.76 Å
- 5IZQ chain H against the predicted model P15328: TM-score 0.98, RMSD 0.76 Å
- 5IZQ chain G against the predicted model P15328: TM-score 0.98, RMSD 1.07 Å
- 5IZQ chain G against the predicted model P15328: TM-score 0.98, RMSD 1.07 Å
- 4LRH chain B against the predicted model P15328: TM-score 0.98, RMSD 0.77 Å
- 4LRH chain B against the predicted model P15328: TM-score 0.98, RMSD 0.77 Å
- 5IZQ chain A against the predicted model P15328: TM-score 0.98, RMSD 1.20 Å
- 5IZQ chain A against the predicted model P15328: TM-score 0.98, RMSD 1.20 Å
Elsewhere
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