UniProt P15170
P15170
P15170 (UniProt P15170): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P15170
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
Structures
9 records of P15170 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3E1Y | Crystal structure of human eRF1/eRF3 complex | x-ray diffraction | E, F, G, H | — | — |
| 3E1Y | Crystal structure of human ERF1/ERF3 complex | x-ray diffraction | E, F, G, H | — | — |
| 3J5Y | Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP | electron microscopy | B | — | — |
| 3J5Y | Structure of the mammalian ribosomal pre-termination complex associated with ERF1-ERF3-gdpnp | electron microscopy | B | — | — |
| 4D61 | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus… | electron microscopy | i | — | — |
| 4D61 | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus… | electron microscopy | i | — | — |
| 5HXB | Cereblon in complex with DDB1, cc-885, and GSPT1 | x-ray diffraction | X, A | — | — |
| 6XK9 | Cereblon in complex with DDB1, cc-90009, and GSPT1 | x-ray diffraction | X, A | V4M | — |
| P15170 | AlphaFold monomer V2.0 prediction for eukaryotic peptide chain release factor GTP-binding subunit… | predicted | A | — | — |
Ligands
- V4M · 2-(4-chlorophenyl)-N-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)-2,2-difluoroacetamide · in 1 record
Experiment against prediction
- 6XK9 chain X against the predicted model P15170: TM-score 0.96, RMSD 1.13 Å
- 6XK9 chain A against the predicted model P15170: TM-score 0.96, RMSD 1.13 Å
- 3E1Y chain H against the predicted model P15170: TM-score 0.96, RMSD 1.14 Å
- 3E1Y chain H against the predicted model P15170: TM-score 0.96, RMSD 1.14 Å
- 3E1Y chain G against the predicted model P15170: TM-score 0.96, RMSD 1.14 Å
- 3E1Y chain G against the predicted model P15170: TM-score 0.96, RMSD 1.14 Å
- 5HXB chain X against the predicted model P15170: TM-score 0.96, RMSD 1.16 Å
- 3E1Y chain E against the predicted model P15170: TM-score 0.96, RMSD 1.18 Å
- 3E1Y chain E against the predicted model P15170: TM-score 0.96, RMSD 1.18 Å
- 3E1Y chain F against the predicted model P15170: TM-score 0.96, RMSD 1.18 Å
Elsewhere
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