UniProt P14920
D-amino-acid oxidase (P14920)
D-amino-acid oxidase (UniProt P14920), EC 1.4.3.3: 41 experimental structures on GenesisL1, 7 ligands bound, 15 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P14920
- Protein
- D-amino-acid oxidase
- EC
- 1.4.3.3
- Experimental structures
- 41
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 15 · 2 records with a druggable one
Structures
41 records of P14920 in the MolNFT archive: 41 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DU8 | Crystal structure of human D-amino acid oxidase | x-ray diffraction | A, B, G, J | — | — |
| 2DU8 | Crystal structure of human D-amino acid oxidase | x-ray diffraction | A, B, G, J | — | — |
| 2E48 | Crystal Structure of Human D-Amino Acid Oxidase: Substrate-Free Holoenzyme | x-ray diffraction | A, B, C, D | — | — |
| 2E48 | Crystal structure of human D-amino acid oxidase: substrate- free holoenzyme | x-ray diffraction | A, B, C, D | — | — |
| 2E49 | Crystal Structure of Human D-Amino Acid Oxidase in Complex with Imino-Serine | x-ray diffraction | A, B, C, D | — | — |
| 2E49 | Crystal structure of human D-amino acid oxidase in complex with imino- serine | x-ray diffraction | A, B, C, D | — | — |
| 2E4A | Crystal Structure of Human D-Amino Acid Oxidase in complex with o-aminobenzoate | x-ray diffraction | A, B, C, D | — | — |
| 2E4A | Crystal structure of human D-amino acid oxidase in complex with O-aminobenzoate | x-ray diffraction | A, B, C, D | — | — |
| 2E82 | Crystal structure of human D-amino acid oxidase complexed with imino-DOPA | x-ray diffraction | A, B, C, D | — | — |
| 2E82 | Crystal structure of human D-amino acid oxidase complexed with imino-dopa | x-ray diffraction | A, B, C, D | — | — |
| 3CUK | Crystal structure of human D-amino acid oxidase: bound to an inhibitor | x-ray diffraction | A, B, C, D | — | — |
| 3CUK | Crystal structure of human D-amino acid oxidase: bound to an inhibitor | x-ray diffraction | A, B, C, D | — | — |
| 3G3E | Crystal structure of human D-amino acid oxidase in complex with hydroxyquinolin-2(1H) | x-ray diffraction | A, B, C, D | — | — |
| 3G3E | Crystal structure of human D-amino acid oxidase in complex with hydroxyquinolin-2(1H) | x-ray diffraction | A, B, C, D | — | — |
| 3W4I | Crystal Structure of human DAAO in complex with coumpound 8 | x-ray diffraction | A, B, C, D | — | — |
| 3W4I | Crystal structure of human daao in complex with coumpound 8 | x-ray diffraction | A, B, C, D | — | — |
| 3W4J | Crystal Structure of human DAAO in complex with coumpound 12 | x-ray diffraction | A, B, C, D | — | — |
| 3W4J | Crystal structure of human daao in complex with coumpound 12 | x-ray diffraction | A, B, C, D | — | — |
| 3W4K | Crystal Structure of human DAAO in complex with coumpound 13 | x-ray diffraction | A, B, C, D | — | — |
| 3W4K | Crystal structure of human daao in complex with coumpound 13 | x-ray diffraction | A, B, C, D | — | — |
| 3ZNN | In vitro and in vivo inhibition of human D-amino acid oxidase: regulation of D-serine concentration… | x-ray diffraction | A, B | — | — |
| 3ZNN | In vitro and in vivo inhibition of human D-amino acid oxidase: regulation of D-serine concentration… | x-ray diffraction | A, B | — | — |
| 3ZNO | In vitro and in vivo inhibition of human D-amino acid oxidase: regulation of D-serine concentration… | x-ray diffraction | A, B | — | — |
| 3ZNO | In vitro and in vivo inhibition of human D-amino acid oxidase: regulation of D-serine concentration… | x-ray diffraction | A, B | — | — |
| 3ZNP | In vitro and in vivo inhibition of human D-amino acid oxidase: regulation of D-serine concentration… | x-ray diffraction | A, B | — | — |
| 3ZNP | In vitro and in vivo inhibition of human D-amino acid oxidase: regulation of D-serine concentration… | x-ray diffraction | A, B | — | — |
| 3ZNQ | In vitro and in vivo inhibition of human D-amino acid oxidase: regulation of D-serine concentration… | x-ray diffraction | A, B | — | — |
| 3ZNQ | In vitro and in vivo inhibition of human D-amino acid oxidase: regulation of D-serine concentration… | x-ray diffraction | A, B | — | — |
| 4QFC | Co-crystal structure of compound 3 (4-hydroxy-6-[2-(7-hydroxy-2-oxo-4-phenyl-2h-chromen-6-yl)ethyl]p… | x-ray diffraction | A, B | — | — |
| 4QFC | Co-crystal structure of compound 3 (4-hydroxy-6-[2-(7-hydroxy-2-oxo-4… | x-ray diffraction | A, B | — | — |
| 4QFD | Co-crystal structure of compound 2 (3-(7-hydroxy-2-oxo-4-phenyl-2H-chromen-6-yl)propanoic acid) and… | x-ray diffraction | A, B | — | — |
| 4QFD | Co-crystal structure of compound 2 (3-(7-hydroxy-2-oxo-4-phenyl-2H- chromen-6-YL)PROPANOIC acid)… | x-ray diffraction | A, B | — | — |
| 5ZJ9 | Human D-amino acid oxidase complexed with 5-chlorothiophene-3- carboxylic acid | x-ray diffraction | A, B, C, D | FAD, 9E6 | — |
| 5ZJA | Human D-amino acid oxidase complexed with 5-chlorothiophene-2- carboxylic acid | x-ray diffraction | A, B, C, D | FAD, 9E9 | — |
| 6KBP | Crystal structure of human D-amino acid oxidase mutant (P219L) complexed with benzoate | x-ray diffraction | A, B, C, D | FAD, BEZ | — |
| 7U9S | Crystal structure of human D-amino acid oxidase in complex with inhibitor | x-ray diffraction | A, B | FAD, M7I | 6 (best 0.90) |
| 7U9S | Crystal structure of human D-amino acid oxidase in complex with inhibitor | x-ray diffraction | A, B | FAD, M7I | — |
| 7U9U | Crystal structure of human D-amino acid oxidase in complex with inhibitor | x-ray diffraction | A, B | FAD, BEZ, M89 | — |
| 7U9U | Crystal structure of human D-amino acid oxidase in complex with inhibitor | x-ray diffraction | A, B | FAD, BEZ, M89 | — |
| 8HY5 | Structure of D-amino acid oxidase mutant R38H | x-ray diffraction | A, B | FAD, BEZ, NA | 9 (best 0.83) |
| P14920 | AlphaFold monomer V2.0 prediction for D-amino-acid oxidase (P14920) | — | — | — |
Ligands
- FAD · Flavin-adenine dinucleotide · in 8 records
- BEZ · Benzoic acid · in 4 records
- M7I · 5-{2-[4-(trifluoromethyl)phenyl]ethyl}-1,4-dihydropyrazine-2,3-dione · in 2 records
- M89 · (3R)-3-(5,6-dioxo-1,4,5,6-tetrahydropyrazin-2-yl)-2,3-dihydro-1,4-benzoxathiine-7-carbonitrile · in 2 records
- 9E6 · 5-chloro thiophene-3-carboxylic acid · in 1 record
- 9E9 · 5-chloro thiophene-2-carboxylic acid · in 1 record
- NA · Sodium ion · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.