UniProt P14908
Mitochondrial transcription factor 1 (P14908)
Mitochondrial transcription factor 1 (UniProt P14908), EC 2.1.1.-: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 24 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P14908
- Protein
- Mitochondrial transcription factor 1
- EC
- 2.1.1.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 24 · 4 records with a druggable one
Structures
9 records of P14908 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1I4W | The crystal structure of the transcription factor sc-mttfb offers intriguing insights into… | x-ray diffraction | A | — | — |
| 1I4W | The crystal structure of the transcription factor sc-mttfb offers intriguing insights into… | x-ray diffraction | A | — | — |
| 6YMV | Cryo-EM structure of yeast mitochondrial RNA polymerase partially- melted transcription initiation… | electron microscopy | B | — | — |
| 6YMW | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex | electron microscopy | B | — | — |
| 8ATT | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 4-mer… | electron microscopy | B | GTP | 6 (best 0.84) |
| 8C5S | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 7-mer… | electron microscopy | B | — | 6 (best 0.84) |
| 8C5U | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 8-mer… | electron microscopy | B | — | 4 (best 0.73) |
| 8Q63 | Cryo-EM structure of IC8', a second state of yeast mitochondrial RNA polymerase transcription… | electron microscopy | B | — | 5 (best 0.67) |
| P14908 | AlphaFold monomer V2.0 prediction for mitochondrial transcription factor 1 (P14908) | predicted | A | — | 3 (best 0.39) |
Ligands
- GTP · Guanosine-5'-triphosphate · in 1 record
Experiment against prediction
- 1I4W chain A against the predicted model P14908: TM-score 0.99, RMSD 0.79 Å
- 1I4W chain A against the predicted model P14908: TM-score 0.99, RMSD 0.79 Å
- 8C5U chain B against the predicted model P14908: TM-score 0.98, RMSD 0.91 Å
- 6YMV chain B against the predicted model P14908: TM-score 0.98, RMSD 1.06 Å
- 8Q63 chain B against the predicted model P14908: TM-score 0.97, RMSD 1.12 Å
- 8C5S chain B against the predicted model P14908: TM-score 0.97, RMSD 1.12 Å
- 6YMW chain B against the predicted model P14908: TM-score 0.96, RMSD 1.10 Å
- 8ATT chain B against the predicted model P14908: TM-score 0.96, RMSD 1.22 Å
Elsewhere
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