UniProt P14585
Protein lin-12 (P14585)
Protein lin-12 (UniProt P14585): 6 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P14585
- Protein
- Protein lin-12
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
7 records of P14585 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FO1 | Crystal Structure of the CSL-Notch-Mastermind ternary complex bound to DNA | x-ray diffraction | E | — | — |
| 2FO1 | Crystal structure of the csl-notch-mastermind ternary complex bound to DNA | x-ray diffraction | E | — | — |
| 3BRD | CSL (Lag-1) bound to DNA with Lin-12 RAM peptide, P212121 | x-ray diffraction | D | — | — |
| 3BRD | Csl (lag-1) bound to DNA with lin-12 ram peptide, P212121 | x-ray diffraction | D | — | — |
| 3BRF | CSL (Lag-1) bound to DNA with Lin-12 RAM peptide, C2221 | x-ray diffraction | D | — | — |
| 3BRF | Csl (lag-1) bound to DNA with lin-12 ram peptide, C2221 | x-ray diffraction | D | — | — |
| P14585 | AlphaFold monomer V2.0 prediction for protein lin-12 (P14585) | predicted | A | — | 7 (best 0.73) |
Experiment against prediction
- 2FO1 chain E against the predicted model P14585: TM-score 0.92, RMSD 2.00 Å
- 2FO1 chain E against the predicted model P14585: TM-score 0.92, RMSD 2.00 Å
- 3BRF chain D against the predicted model P14585: TM-score 0.35, RMSD 1.57 Å
- 3BRF chain D against the predicted model P14585: TM-score 0.35, RMSD 1.57 Å
- 3BRD chain D against the predicted model P14585: TM-score 0.29, RMSD 1.29 Å
- 3BRD chain D against the predicted model P14585: TM-score 0.29, RMSD 1.29 Å
Elsewhere
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