UniProt P14483
H-2 class II histocompatibility antigen, A beta chain (P14483)
H-2 class II histocompatibility antigen, A beta chain (UniProt P14483), EC 3.5.3.15: 28 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P14483
- Protein
- H-2 class II histocompatibility antigen, A beta chain
- EC
- 3.5.3.15
- Experimental structures
- 28
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
29 records of P14483 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1LNU | CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IAb BOUND TO EALPHA3K PEPTIDE | x-ray diffraction | B, D, F, H | — | — |
| 1LNU | Crystal structure of class II MHC molecule iab bound to EALPHA3K peptide | x-ray diffraction | B, D, F, H | — | — |
| 1MUJ | Crystal structure of murine class II MHC I-Ab in complex with a human CLIP peptide | x-ray diffraction | B | — | — |
| 1MUJ | Crystal structure of murine class II MHC I-ab in complex with a human clip peptide | x-ray diffraction | B | — | — |
| 3C5Z | Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR B3K506 | x-ray diffraction | D, H | — | — |
| 3C5Z | Crystal structure of mouse MHC class II I-AB/3K peptide complexed with mouse TCR B3K506 | x-ray diffraction | D, H | — | — |
| 3C60 | Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR YAe62 | x-ray diffraction | D, H | — | — |
| 3C60 | Crystal structure of mouse MHC class II I-AB/3K peptide complexed with mouse TCR YAE62 | x-ray diffraction | D, H | — | — |
| 3C6L | Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR 2W20 | x-ray diffraction | D, H | — | — |
| 3C6L | Crystal structure of mouse MHC class II I-AB/3K peptide complexed with mouse TCR 2W20 | x-ray diffraction | D, H | — | — |
| 3RDT | Crystal Structure of 809.B5 TCR complexed with MHC Class II I-Ab/3k peptide | x-ray diffraction | D | — | — |
| 3RDT | Crystal structure of 809.B5 TCR complexed with MHC class II I-AB/3K peptide | x-ray diffraction | D | — | — |
| 4P23 | J809.B5 TCR bound to IAb/3K | x-ray diffraction | D | — | — |
| 4P23 | J809.B5 TCR bound to IAB/3K | x-ray diffraction | D | — | — |
| 4P46 | J809.B5 Y31A TCR bound to IAb3K | x-ray diffraction | D | — | — |
| 4P46 | J809.B5 Y31A TCR bound to IAB3K | x-ray diffraction | D | — | — |
| 4P5T | 14.C6 TCR complexed with MHC class II I-Ab/3K peptide | x-ray diffraction | D, H | — | — |
| 4P5T | 14.C6 TCR complexed with MHC class II I-AB/3K peptide | x-ray diffraction | D, H | — | — |
| 6MKD | 4699 TCR bound to I-Ab Padi4 | x-ray diffraction | D | — | — |
| 6MKD | 4699 TCR bound to I-ab PADI4 | x-ray diffraction | D | — | — |
| 6MKR | 5287 TCR bound to IAb Padi4 | x-ray diffraction | D | — | — |
| 6MKR | 5287 TCR bound to iab PADI4 | x-ray diffraction | D | — | — |
| 6MNG | 4738 TCR bound to iab PADI4 | x-ray diffraction | D | — | — |
| 6MNM | 6256 TCR bound to I-Ab Padi4 | x-ray diffraction | D | — | 5 (best 0.67) |
| 6MNM | 6256 TCR bound to I-ab PADI4 | x-ray diffraction | D | — | — |
| 6MNN | 6236 TCR bound to I-ab PADI4 | x-ray diffraction | D | — | — |
| 6MNO | 6235 TCR bound to I-ab PADI4 | x-ray diffraction | D | — | — |
| 8RAL | CL3E peptide bound to the I-Ab murine MHC class II receptor | x-ray diffraction | B | — | 1 (best 0.40) |
| P14483 | AlphaFold monomer V2.0 prediction for H-2 class II histocompatibility antigen, a beta chain (P14483) | predicted | A | — | — |
Experiment against prediction
- 1MUJ chain B against the predicted model P14483: TM-score 0.82, RMSD 2.43 Å
- 1MUJ chain B against the predicted model P14483: TM-score 0.82, RMSD 2.43 Å
- 8RAL chain B against the predicted model P14483: TM-score 0.81, RMSD 2.46 Å
- 3C6L chain D against the predicted model P14483: TM-score 0.78, RMSD 2.50 Å
- 3C6L chain D against the predicted model P14483: TM-score 0.78, RMSD 2.50 Å
- 6MNG chain D against the predicted model P14483: TM-score 0.75, RMSD 2.60 Å
- 3C5Z chain D against the predicted model P14483: TM-score 0.75, RMSD 2.69 Å
- 3C5Z chain D against the predicted model P14483: TM-score 0.75, RMSD 2.69 Å
- 6MNN chain D against the predicted model P14483: TM-score 0.75, RMSD 2.61 Å
- 6MNM chain D against the predicted model P14483: TM-score 0.74, RMSD 2.64 Å
Elsewhere
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