UniProt P13693
Translationally-controlled tumor protein (P13693)
Translationally-controlled tumor protein (UniProt P13693): 16 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P13693
- Protein
- Translationally-controlled tumor protein
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
17 records of P13693 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1YZ1 | Crystal structure of human translationally controlled tumour associated protein | x-ray diffraction | A, B, C, D | — | — |
| 1YZ1 | Crystal structure of human translationally controlled tumour associated protein | x-ray diffraction | A, B, C, D | — | — |
| 2HR9 | Solution structure of human translationally controlled tumor protein | solution nmr | A | — | — |
| 2HR9 | Solution structure of human translationally controlled tumor protein | solution nmr | A | — | — |
| 3EBM | Crystal structure of human translationally controlled tumour associated protein (hTCTP) mutant E12V | x-ray diffraction | A, B, C, D | — | — |
| 3EBM | Crystal structure of human translationally controlled tumour associated protein (htctp) mutant E12V | x-ray diffraction | A, B, C, D | — | — |
| 4Z9V | TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL | x-ray diffraction | C, D, E, F, G, H | — | — |
| 4Z9V | Tctp contains a BH3-like domain, which instead of inhibiting, activates BCL-xl | x-ray diffraction | C, D, E, F, G, H | — | — |
| 5O9L | Crystal structure of human Histamine-Releasing Factor (HRF/TCTP) | x-ray diffraction | A, B | — | 2 (best 0.61) |
| 5O9L | Crystal structure of human histamine-releasing factor (HRF/TCTP) | x-ray diffraction | A, B | — | — |
| 5O9M | Crystal structure of human Histamine-Releasing Factor (HRF/TCTP)containing a disulphide-linked dimer | x-ray diffraction | A, B | — | 2 (best 0.37) |
| 5O9M | Crystal structure of human histamine-releasing factor (HRF/TCTP) containing a disulphide-linked… | x-ray diffraction | A, B | — | — |
| 6IZB | Flexible loop truncated human TCTP | x-ray diffraction | A | — | — |
| 6IZB | Flexible loop truncated human tctp | x-ray diffraction | A | — | — |
| 6IZE | Dimeric human TCTP | x-ray diffraction | A, B, C, D | — | — |
| 6IZE | Dimeric human tctp | x-ray diffraction | A, B, C, D | — | — |
| P13693 | AlphaFold monomer V2.0 prediction for translationally-controlled tumor protein (P13693) | predicted | A | — | — |
Experiment against prediction
- 6IZE chain A against the predicted model P13693: TM-score 0.98, RMSD 0.60 Å
- 6IZE chain A against the predicted model P13693: TM-score 0.98, RMSD 0.60 Å
- 1YZ1 chain D against the predicted model P13693: TM-score 0.98, RMSD 0.42 Å
- 1YZ1 chain D against the predicted model P13693: TM-score 0.98, RMSD 0.42 Å
- 3EBM chain D against the predicted model P13693: TM-score 0.98, RMSD 0.45 Å
- 3EBM chain D against the predicted model P13693: TM-score 0.98, RMSD 0.45 Å
- 1YZ1 chain B against the predicted model P13693: TM-score 0.97, RMSD 0.50 Å
- 1YZ1 chain B against the predicted model P13693: TM-score 0.97, RMSD 0.50 Å
- 1YZ1 chain A against the predicted model P13693: TM-score 0.97, RMSD 0.56 Å
- 1YZ1 chain A against the predicted model P13693: TM-score 0.97, RMSD 0.56 Å
Elsewhere
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