UniProt P11310
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (P11310)
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (UniProt P11310), EC 1.3.8.7: 13 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 15 pockets. Binding sites, druggability and experiment…
- UniProt
- P11310
- Protein
- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
- EC
- 1.3.8.7
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 15 · 1 record with a druggable one
Structures
14 records of P11310 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EGC | Structure of T255E, E376G mutant of human medium chain acyl-CoA dehydrogenase complexed with… | x-ray diffraction | A, B, C, D | — | — |
| 1EGC | Structure of T255E, E376G mutant of human medium chain acyl-CoA dehydrogenase complexed with… | x-ray diffraction | A, B, C, D | — | — |
| 1EGD | Structure of T255E, E376G mutant of human medium chain acyl-CoA dehydrogenase | x-ray diffraction | A, B, C, D | — | — |
| 1EGD | Structure of T255E, E376G mutant of human medium chain acyl-CoA dehydrogenase | x-ray diffraction | A, B, C, D | — | — |
| 1EGE | Structure of T255E, E376G mutant of human medium chain acyl-CoA dehydrogenase | x-ray diffraction | A, B, C, D | — | — |
| 1EGE | Structure of T255E, E376G mutant of human medium chain acyl- CoA dehydrogenase | x-ray diffraction | A, B, C, D | — | — |
| 1T9G | Structure of the human MCAD:ETF complex | x-ray diffraction | A, B, C, D | — | — |
| 1T9G | Structure of the human MCAD:ETF complex | x-ray diffraction | A, B, C, D | — | — |
| 2A1T | Structure of the human MCAD:ETF E165betaA complex | x-ray diffraction | A, B, C, D | — | — |
| 2A1T | Structure of the human MCAD:ETF E165BETAA complex | x-ray diffraction | A, B, C, D | — | — |
| 4P13 | Medium chain acyl-CoA dehydrogenase, K304E mutant | x-ray diffraction | A, B, C, D | — | — |
| 4P13 | Medium chain acyl-CoA dehydrogenase, K304E mutant | x-ray diffraction | A, B, C, D | — | — |
| 8SGP | human liver mitochondrial Medium-chain specific acyl-CoA dehydrogenase | electron microscopy | A, B, C, D | FAD | 15 (best 0.84) |
| P11310 | AlphaFold monomer V2.0 prediction for medium-chain specific acyl-CoA dehydrogenase, mitochondrial… | predicted | A | — | — |
Ligands
- FAD · Flavin-adenine dinucleotide · in 1 record
Experiment against prediction
- 4P13 chain B against the predicted model P11310: TM-score 1.00, RMSD 0.25 Å
- 4P13 chain B against the predicted model P11310: TM-score 1.00, RMSD 0.25 Å
- 4P13 chain D against the predicted model P11310: TM-score 1.00, RMSD 0.25 Å
- 4P13 chain A against the predicted model P11310: TM-score 1.00, RMSD 0.30 Å
- 4P13 chain A against the predicted model P11310: TM-score 1.00, RMSD 0.30 Å
- 2A1T chain A against the predicted model P11310: TM-score 1.00, RMSD 0.31 Å
- 2A1T chain A against the predicted model P11310: TM-score 1.00, RMSD 0.31 Å
- 2A1T chain B against the predicted model P11310: TM-score 1.00, RMSD 0.33 Å
- 2A1T chain B against the predicted model P11310: TM-score 1.00, RMSD 0.33 Å
- 1T9G chain A against the predicted model P11310: TM-score 1.00, RMSD 0.34 Å
Elsewhere
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