UniProt P11166
Solute carrier family 2, facilitated glucose transporter member 1 (P11166)
Solute carrier family 2, facilitated glucose transporter member 1 (UniProt P11166): 10 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 11 pockets. Binding sites, druggability and experiment against…
- UniProt
- P11166
- Protein
- Solute carrier family 2, facilitated glucose transporter member 1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 11 · 3 records with a druggable one
Structures
11 records of P11166 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4PYP | Crystal structure of the human glucose transporter GLUT1 | x-ray diffraction | A | — | — |
| 4PYP | Crystal structure of the human glucose transporter GLUT1 | x-ray diffraction | A | — | — |
| 5EQG | Human GLUT1 in complex with inhibitor (2~{S})-3-(4-fluorophenyl)-2-[2-(3-hydroxyphenyl)ethanoylamino… | x-ray diffraction | A | 5RE | — |
| 5EQG | Human GLUT1 in complex with inhibitor (2~{S})-3-(4-fluorophenyl)-2-[2… | x-ray diffraction | A | — | — |
| 5EQH | Human GLUT1 in complex with inhibitor (2~{S})-3-(2-bromophenyl)-2-[2-(4-methoxyphenyl)ethanoylamino]… | x-ray diffraction | A | 5RF | 4 (best 0.78) |
| 5EQH | Human GLUT1 in complex with inhibitor (2~{S})-3-(2-bromophenyl)-2-[2… | x-ray diffraction | A | — | — |
| 5EQI | Human GLUT1 in complex with Cytochalasin B | x-ray diffraction | A | 5RH | — |
| 5EQI | Human GLUT1 in complex with cytochalasin B | x-ray diffraction | A | — | — |
| 6THA | Crystal structure of human sugar transporter GLUT1 (SLC2A1) in the inward conformation | x-ray diffraction | A | BNG, CL | 4 (best 0.78) |
| 6THA | Crystal structure of human sugar transporter GLUT1 (SLC2A1) in the inward conformation | x-ray diffraction | A | BNG, CL | — |
| P11166 | AlphaFold monomer V2.0 prediction for solute carrier family 2, facilitated glucose transporter… | predicted | A | — | 3 (best 0.77) |
Ligands
- BNG · nonyl beta-D-glucopyranoside · in 2 records
- CL · Chloride ion · in 2 records
- 5RE · (2~{S})-3-(4-fluorophenyl)-2-[2-(3-hydroxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide · in 1 record
- 5RF · (2~{S})-3-(2-bromophenyl)-2-[2-(4-methoxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide · in 1 record
- 5RH · Cytochalasin B · in 1 record
Experiment against prediction
- 6THA chain A against the predicted model P11166: TM-score 0.86, RMSD 3.25 Å
- 6THA chain A against the predicted model P11166: TM-score 0.86, RMSD 3.25 Å
- 5EQH chain A against the predicted model P11166: TM-score 0.86, RMSD 3.29 Å
- 5EQH chain A against the predicted model P11166: TM-score 0.86, RMSD 3.29 Å
- 5EQG chain A against the predicted model P11166: TM-score 0.86, RMSD 3.30 Å
- 5EQG chain A against the predicted model P11166: TM-score 0.86, RMSD 3.30 Å
- 4PYP chain A against the predicted model P11166: TM-score 0.85, RMSD 3.30 Å
- 4PYP chain A against the predicted model P11166: TM-score 0.85, RMSD 3.30 Å
- 5EQI chain A against the predicted model P11166: TM-score 0.84, RMSD 3.48 Å
- 5EQI chain A against the predicted model P11166: TM-score 0.84, RMSD 3.48 Å
Elsewhere
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