UniProt P10584
Malate dehydrogenase (P10584)
Malate dehydrogenase (UniProt P10584), EC 1.1.1.37: 18 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 51 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P10584
- Protein
- Malate dehydrogenase
- EC
- 1.1.1.37
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 51 · 8 records with a druggable one
Structures
19 records of P10584 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BDM | The structure at 1.8 ångströms resolution of a single site mutant (T189I) of malate dehydrogenase… | x-ray diffraction | A, B | NAX | 8 (best 0.55) |
| 1BDM | The structure at 1.8 ångströms resolution of a single site mutant (T189I) of malate dehydrogenase… | x-ray diffraction | A, B | — | — |
| 1BMD | Determinants of protein thermostability observed in the 1.9 ångströms crystal structure of malate… | x-ray diffraction | A, B | NAD | 7 (best 0.59) |
| 1BMD | Determinants of protein thermostability observed in the 1.9 ångströms crystal structure of malate… | x-ray diffraction | A, B | — | — |
| 1IZ9 | Crystal Structure of Malate Dehydrogenase from Thermus thermophilus HB8 | x-ray diffraction | A, B | — | 7 (best 0.60) |
| 1IZ9 | Crystal structure of malate dehydrogenase from thermus thermophilus HB8 | x-ray diffraction | A, B | — | — |
| 1WZE | Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus | x-ray diffraction | A, B | NAD | 7 (best 0.61) |
| 1WZE | Structural basis for alteration of cofactor specificity of malate dehydrogenase from thermus flavus | x-ray diffraction | A, B | — | — |
| 1WZI | Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus | x-ray diffraction | A, B | NDP | 7 (best 0.58) |
| 1WZI | Structural basis for alteration of cofactor specificity of malate dehydrogenase from thermus flavus | x-ray diffraction | A, B | — | — |
| 1Y7T | Crystal structure of NAD(H)-depenent malate dehydrogenase complexed with NADPH | x-ray diffraction | A, B | NDP | 7 (best 0.63) |
| 1Y7T | Crystal structure of NAD(H)-depenent malate dehydrogenase complexed with NADPH | x-ray diffraction | A, B | — | — |
| 2CVQ | Crystal structure of NAD(H)-dependent malate dehydrogenase complexed with NADPH | x-ray diffraction | A, B | NDP | 7 (best 0.61) |
| 2CVQ | Crystal structure of NAD(H)-dependent malate dehydrogenase complexed with NADPH | x-ray diffraction | A, B | — | — |
| 4KDE | Crystal Structure of the Apo Form of Thermus thermophilus Malate Dehydrogenase | x-ray diffraction | A, B | — | — |
| 4KDE | Crystal structure of the apo form of thermus thermophilus malate dehydrogenase | x-ray diffraction | A, B | — | — |
| 4KDF | Crystal Structure of Thermus thermophilus Malate Dehydrogenase in Complex with NAD | x-ray diffraction | A, B, C, D | — | — |
| 4KDF | Crystal structure of thermus thermophilus malate dehydrogenase in complex with NAD | x-ray diffraction | A, B, C, D | — | — |
| P10584 | AlphaFold monomer V2.0 prediction for malate dehydrogenase (P10584) | predicted | A | — | 1 (best 0.62) |
Ligands
Experiment against prediction
- 1WZI chain A against the predicted model P10584: TM-score 1.00, RMSD 0.43 Å
- 1WZI chain A against the predicted model P10584: TM-score 1.00, RMSD 0.43 Å
- 1BDM chain A against the predicted model P10584: TM-score 1.00, RMSD 0.44 Å
- 1BDM chain A against the predicted model P10584: TM-score 1.00, RMSD 0.44 Å
- 4KDF chain C against the predicted model P10584: TM-score 1.00, RMSD 0.50 Å
- 4KDF chain C against the predicted model P10584: TM-score 1.00, RMSD 0.50 Å
- 4KDE chain B against the predicted model P10584: TM-score 0.99, RMSD 0.50 Å
- 4KDE chain B against the predicted model P10584: TM-score 0.99, RMSD 0.50 Å
- 1BMD chain A against the predicted model P10584: TM-score 0.99, RMSD 0.49 Å
- 1BMD chain A against the predicted model P10584: TM-score 0.99, RMSD 0.49 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.