UniProt P0DP24
Calmodulin-2 (P0DP24)
Calmodulin-2 (UniProt P0DP24): 17 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 54 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0DP24
- Protein
- Calmodulin-2
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 54 · 7 records with a druggable one
Structures
18 records of P0DP24 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6PLM | Legionella pneumophila sidj/ calmodulin 2 complex | x-ray diffraction | C, D | CA | — |
| 6S5T | Legionella pneumophila SidJ-Human calmodulin complex | electron microscopy | B | — | 5 (best 0.73) |
| 6S5T | Legionella pneumophila sidj-human calmodulin complex | electron microscopy | B | — | — |
| 6SZ5 | Human calmodulin bound to a peptide of human NADPH oxidase 5 | x-ray diffraction | A | CA | 2 (best 0.35) |
| 6SZ5 | Human calmodulin bound to a peptide of human NADPH oxidase 5 | x-ray diffraction | A | CA | — |
| 6Y4O | Calmodulin bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain | x-ray diffraction | A | CA | 1 (best 0.49) |
| 6Y4O | Calmodulin bound to cardiac ryanodine receptor (RYR2) calmodulin binding domain | x-ray diffraction | A | CA | — |
| 7MIR | Cryo-EM structure of SidJ-SdeA-CaM reaction intermediate complex | electron microscopy | B | CA | 4 (best 0.78) |
| 7MIR | Cryo-EM structure of sidj-sdea-cam reaction intermediate complex | electron microscopy | B | CA | — |
| 7MIS | Cryo-EM structure of SidJ-SdeC-CaM reaction intermediate complex | electron microscopy | B | CA | 4 (best 0.76) |
| 7MIS | Cryo-EM structure of sidj-sdec-cam reaction intermediate complex | electron microscopy | B | CA | — |
| 7PPO | Structure of SidJ/CaM bound to SdeA in pre-glutamylation state | electron microscopy | B | CA | 4 (best 0.72) |
| 7PPO | Structure of SIDJ/CAM bound to sdea in pre-glutamylation state | electron microscopy | B | CA | — |
| 7PQE | Structure of SidJ/CaM bound to SdeA in post-catalysis state | electron microscopy | B | CA | 3 (best 0.75) |
| 7PQE | Structure of SIDJ/CAM bound to sdea in post-catalysis state | electron microscopy | B | CA | — |
| 8KA0 | Crystal structure of Vibrio vulnificus RID-dependent transforming NADase domain… | x-ray diffraction | B, D, F, H | CA | 16 (best 0.76) |
| 8KA1 | Crystal structure of Vibrio vulnificus RID-dependent transforming NADase domain… | x-ray diffraction | B, D, F, H | MG | 15 (best 0.64) |
| P0DP24 | AlphaFold monomer V2.0 prediction for calmodulin-2 (P0DP24) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6SZ5 chain A against the predicted model P0DP24: TM-score 0.84, RMSD 2.13 Å
- 6SZ5 chain A against the predicted model P0DP24: TM-score 0.84, RMSD 2.13 Å
- 6Y4O chain A against the predicted model P0DP24: TM-score 0.51, RMSD 1.35 Å
- 6Y4O chain A against the predicted model P0DP24: TM-score 0.51, RMSD 1.35 Å
- 7PQE chain B against the predicted model P0DP24: TM-score 0.43, RMSD 3.70 Å
- 7PQE chain B against the predicted model P0DP24: TM-score 0.43, RMSD 3.70 Å
- 7MIR chain B against the predicted model P0DP24: TM-score 0.43, RMSD 3.87 Å
- 7MIR chain B against the predicted model P0DP24: TM-score 0.43, RMSD 3.87 Å
- 7MIS chain B against the predicted model P0DP24: TM-score 0.42, RMSD 4.10 Å
- 7MIS chain B against the predicted model P0DP24: TM-score 0.42, RMSD 4.10 Å
Elsewhere
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