UniProt P0CH28
Polyubiquitin-C (P0CH28)
Polyubiquitin-C (UniProt P0CH28), EC 2.7.7.49: 8 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0CH28
- Protein
- Polyubiquitin-C
- EC
- 2.7.7.49
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
9 records of P0CH28 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4XKH | Crystal structure of the airapl tandem uims in complex with a LYS48-linked tri-ubiquitin | x-ray diffraction | A, F, B, D, G, I | — | — |
| 4XKH | Crystal structure of the airapl tandem uims in complex with a LYS48- linked tri-ubiquitin | x-ray diffraction | A, F, B, D, G, I | — | — |
| 4XYZ | Crystal structure of K33 linked di-Ubiquitin | x-ray diffraction | A, B | — | — |
| 4XYZ | Crystal structure of K33 linked di-ubiquitin | x-ray diffraction | A, B | — | — |
| 5AIT | A complex of of RNF4-RING domain, UbeV2, Ubc13-Ub (isopeptide crosslink) | x-ray diffraction | C, F | — | — |
| 5AIT | A complex of of RNF4-ring domain, UBEV2, UBC13-ub (isopeptide crosslink) | x-ray diffraction | C, F | — | — |
| 6A42 | R1EN(5-223)-ubiquitin fusion | x-ray diffraction | A | — | 2 (best 0.55) |
| 6A42 | R1EN(5-223)-ubiquitin fusion | x-ray diffraction | A | — | — |
| P0CH28 | AlphaFold monomer V2.0 prediction for polyubiquitin-C (P0CH28) | predicted | A | — | — |
Experiment against prediction
- 4XKH chain F against the predicted model P0CH28: TM-score 0.97, RMSD 0.59 Å
- 4XKH chain F against the predicted model P0CH28: TM-score 0.97, RMSD 0.59 Å
- 4XYZ chain A against the predicted model P0CH28: TM-score 0.97, RMSD 0.63 Å
- 4XYZ chain A against the predicted model P0CH28: TM-score 0.97, RMSD 0.63 Å
- 4XKH chain A against the predicted model P0CH28: TM-score 0.96, RMSD 0.63 Å
- 4XKH chain A against the predicted model P0CH28: TM-score 0.96, RMSD 0.63 Å
- 4XKH chain B against the predicted model P0CH28: TM-score 0.96, RMSD 0.67 Å
- 4XKH chain B against the predicted model P0CH28: TM-score 0.96, RMSD 0.67 Å
- 4XYZ chain B against the predicted model P0CH28: TM-score 0.94, RMSD 0.84 Å
- 4XYZ chain B against the predicted model P0CH28: TM-score 0.94, RMSD 0.84 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.