UniProt P0C6X5
3C-like proteinase (P0C6X5)
3C-like proteinase (UniProt P0C6X5), EC 3.4.22.-: 7 experimental structures on GenesisL1, 6 ligands bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P0C6X5
- Protein
- 3C-like proteinase
- EC
- 3.4.22.-
- Experimental structures
- 7
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 21 · 3 records with a druggable one
Structures
7 records of P0C6X5 in the MolNFT archive: 7 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5NH0 | Structure of human coronavirus NL63 main protease in complex with the alpha-ketoamide tert-Butyl… | x-ray diffraction | A, B, C | 8X8 | 10 (best 0.80) |
| 5NH0 | Structure of human coronavirus NL63 main protease in complex with the alpha-ketoamide tert-butyl… | x-ray diffraction | A, B, C | 8X8 | — |
| 6FV1 | Structure of human coronavirus NL63 main protease in complex with the alpha-ketoamide… | x-ray diffraction | A, B, C | E8E, SO4 | 7 (best 0.79) |
| 6FV1 | Structure of human coronavirus NL63 main protease in complex with the alpha-ketoamide… | x-ray diffraction | A, B, C | E8E, SO4 | — |
| 6FV2 | Structure of human coronavirus NL63 main protease in complex with the alpha-ketoamide… | x-ray diffraction | A, B, C | D03 | — |
| 7WQH | Crystal structure of hcov-NL63 main protease with PF07304814 | x-ray diffraction | A, B | 80I | — |
| 8HUU | Crystal structure of HCoV-NL63 main protease with S217622 | x-ray diffraction | A, B | 7YY | 4 (best 0.72) |
Ligands
- 8X8 · ~{tert}-butyl ~{N}-[(2~{S},3~{R})-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]carbamate · in 2 records
- E8E · (2~{S})-4-methyl-~{N}-[(2~{S},3~{R})-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]pentanamide · in 2 records
- SO4 · Sulfate ion · in 2 records
- 7YY · 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione · in 1 record
- 80I · [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl) carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate · in 1 record
- D03 · (S)-N-benzyl-3-((S)-2-cinnamamido-3-phenylpropanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanamide · in 1 record
Elsewhere
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