UniProt P0C6T2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (P0C6T2)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (UniProt P0C6T2): 7 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 2 pockets. Binding sites, druggability and experiment…
- UniProt
- P0C6T2
- Protein
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 2 · 2 records with a druggable one
Structures
8 records of P0C6T2 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LAT | Solution structure of a Human minimembrane protein OST4 | solution nmr | A | — | — |
| 2LAT | Solution structure of a human minimembrane protein OST4 | solution nmr | A | — | — |
| 6S7O | Cryo-EM structure of human oligosaccharyltransferase complex OST-A | electron microscopy | B | EGY | 1 (best 0.59) |
| 6S7O | Cryo-EM structure of human oligosaccharyltransferase complex ost-a | electron microscopy | B | EGY | — |
| 6S7T | Cryo-EM structure of human oligosaccharyltransferase complex OST-B | electron microscopy | B | EGY | — |
| 6S7T | Cryo-EM structure of human oligosaccharyltransferase complex ost-B | electron microscopy | B | EGY | — |
| 8PN9 | Structure of human oligosaccharyltransferase OST-A complex bound to NGI-1 | electron microscopy | B | — | 1 (best 0.65) |
| P0C6T2 | AlphaFold monomer V2.0 prediction for dolichyl- diphosphooligosaccharide--protein… | predicted | A | — | — |
Ligands
- EGY · (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium · in 4 records
Experiment against prediction
- 6S7T chain B against the predicted model P0C6T2: TM-score 0.90, RMSD 0.63 Å
- 6S7T chain B against the predicted model P0C6T2: TM-score 0.90, RMSD 0.63 Å
- 8PN9 chain B against the predicted model P0C6T2: TM-score 0.88, RMSD 0.68 Å
- 6S7O chain B against the predicted model P0C6T2: TM-score 0.84, RMSD 0.86 Å
- 6S7O chain B against the predicted model P0C6T2: TM-score 0.84, RMSD 0.86 Å
- 2LAT chain A against the predicted model P0C6T2: TM-score 0.51, RMSD 1.73 Å
- 2LAT chain A against the predicted model P0C6T2: TM-score 0.51, RMSD 1.73 Å
Elsewhere
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