UniProt P0AFG9
Pyruvate dehydrogenase E1 component (P0AFG9)
Pyruvate dehydrogenase E1 component (UniProt P0AFG9): 6 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AFG9
- Protein
- Pyruvate dehydrogenase E1 component
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
7 records of P0AFG9 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3LPL | E. coli pyruvate dehydrogenase complex E1 component E571A mutant | x-ray diffraction | A, B | — | — |
| 3LPL | E. COLI pyruvate dehydrogenase complex E1 component E571A mutant | x-ray diffraction | A, B | — | — |
| 3LQ2 | E. coli pyruvate dehydrogenase complex E1 E235A mutant with low TDP concentration | x-ray diffraction | A, B | — | — |
| 3LQ2 | E. COLI pyruvate dehydrogenase complex E1 E235A mutant with low tdp concentration | x-ray diffraction | A, B | — | — |
| 3LQ4 | E. coli pyruvate dehydrogenase complex E1 E235A mutant with high TDP concentration | x-ray diffraction | A, B | — | — |
| 3LQ4 | E. COLI pyruvate dehydrogenase complex E1 E235A mutant with high tdp concentration | x-ray diffraction | A, B | — | — |
| P0AFG9 | AlphaFold monomer V2.0 prediction for pyruvate dehydrogenase E1 component (P0AFG9) | predicted | A | — | 7 (best 0.70) |
Experiment against prediction
- 3LPL chain A against the predicted model P0AFG9: TM-score 1.00, RMSD 0.37 Å
- 3LPL chain A against the predicted model P0AFG9: TM-score 1.00, RMSD 0.37 Å
- 3LQ4 chain A against the predicted model P0AFG9: TM-score 1.00, RMSD 0.40 Å
- 3LQ4 chain A against the predicted model P0AFG9: TM-score 1.00, RMSD 0.40 Å
- 3LQ2 chain A against the predicted model P0AFG9: TM-score 1.00, RMSD 0.54 Å
- 3LQ2 chain A against the predicted model P0AFG9: TM-score 1.00, RMSD 0.54 Å
Elsewhere
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