UniProt P0AFA1
Lipopolysaccharide export system permease protein LptF (P0AFA1)
Lipopolysaccharide export system permease protein LptF (UniProt P0AFA1): 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P0AFA1
- Protein
- Lipopolysaccharide export system permease protein LptF
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 6 · 2 records with a druggable one
Structures
5 records of P0AFA1 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6S8H | Cryo-EM structure of LptB2FG in complex with LPS | electron microscopy | F | LMN, JSG, DCQ | 3 (best 0.74) |
| 6S8H | Cryo-EM structure of LPTB2FG in complex with lps | electron microscopy | F | LMN, JSG, DCQ | — |
| 6S8N | Cryo-EM structure of LptB2FGC in complex with lipopolysaccharide | electron microscopy | F | DCQ, LMN, L0W | 3 (best 0.71) |
| 6S8N | Cryo-EM structure of LPTB2FGC in complex with lipopolysaccharide | electron microscopy | F | DCQ, LMN, L0W | — |
| P0AFA1 | AlphaFold monomer V2.0 prediction for lipopolysaccharide export system permease protein lptf… | predicted | A | — | — |
Ligands
- DCQ · 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione · in 4 records
- LMN · Lauryl Maltose Neopentyl Glycol · in 4 records
- JSG · (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl) ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R}, 6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R}, 3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S}, 4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3, 4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R}) · in 2 records
- L0W · lipopolysaccharide fragment · in 2 records
Experiment against prediction
- 6S8N chain F against the predicted model P0AFA1: TM-score 0.98, RMSD 0.97 Å
- 6S8N chain F against the predicted model P0AFA1: TM-score 0.98, RMSD 0.97 Å
- 6S8H chain F against the predicted model P0AFA1: TM-score 0.96, RMSD 1.28 Å
- 6S8H chain F against the predicted model P0AFA1: TM-score 0.96, RMSD 1.28 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.