UniProt P0ADF8
Acetolactate synthase isozyme 1 small subunit (P0ADF8)
Acetolactate synthase isozyme 1 small subunit (UniProt P0ADF8), EC 2.2.1.6: 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P0ADF8
- Protein
- Acetolactate synthase isozyme 1 small subunit
- EC
- 2.2.1.6
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 15 · 3 records with a druggable one
Structures
11 records of P0ADF8 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LVW | Solution NMR studies of the dimeric regulatory subunit IlvN of the E.coli Acetohydroxyacid synthase… | solution nmr | A, B | — | — |
| 2LVW | Solution NMR studies of the dimeric regulatory subunit ilvn of the E.COLI acetohydroxyacid synthase… | solution nmr | A, B | — | — |
| 5YPP | Crystal structure of IlvN.Val-1a | x-ray diffraction | A, B, C, D, E, F | VAL | 3 (best 0.82) |
| 5YPP | Crystal structure of ILVN.VAL-1A | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5YPY | Crystal structure of IlvN. Val-1c | x-ray diffraction | A, B, C, D | VAL | 3 (best 0.57) |
| 5YPY | Crystal structure of ilvn. val-1C | x-ray diffraction | A, B, C, D | — | — |
| 5YUM | Crystallographic structures of IlvN.Val/Ile complexes:Conformational selectivity for feedback… | x-ray diffraction | A | ILE, CO | — |
| 5YUM | Crystallographic structures of ILVN.VAL/ILE COMPLEXES:CONFORMATIONAL selectivity for feedback… | x-ray diffraction | A | CO | — |
| 6LPI | Crystal Structure of AHAS holo-enzyme | x-ray diffraction | E, F, G, H | — | 9 (best 0.85) |
| 6LPI | Crystal structure of ahas holo-enzyme | x-ray diffraction | E, F, G, H | — | — |
| P0ADF8 | AlphaFold monomer V2.0 prediction for acetolactate synthase isozyme 1 small subunit (P0ADF8) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5YPY chain B against the predicted model P0ADF8: TM-score 0.88, RMSD 1.71 Å
- 5YPY chain A against the predicted model P0ADF8: TM-score 0.88, RMSD 2.01 Å
- 5YPP chain A against the predicted model P0ADF8: TM-score 0.88, RMSD 1.92 Å
- 5YPP chain B against the predicted model P0ADF8: TM-score 0.87, RMSD 1.96 Å
- 5YPP chain E against the predicted model P0ADF8: TM-score 0.87, RMSD 1.96 Å
- 5YPY chain B against the predicted model P0ADF8: TM-score 0.87, RMSD 1.71 Å
- 5YPY chain A against the predicted model P0ADF8: TM-score 0.87, RMSD 2.01 Å
- 5YPP chain F against the predicted model P0ADF8: TM-score 0.87, RMSD 1.82 Å
- 5YUM chain A against the predicted model P0ADF8: TM-score 0.86, RMSD 2.13 Å
- 5YPP chain E against the predicted model P0ADF8: TM-score 0.86, RMSD 1.96 Å
Elsewhere
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