UniProt P0AC41
Succinate dehydrogenase flavoprotein subunit (P0AC41)
Succinate dehydrogenase flavoprotein subunit (UniProt P0AC41), EC 1.3.5.1: 22 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 38 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P0AC41
- Protein
- Succinate dehydrogenase flavoprotein subunit
- EC
- 1.3.5.1
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 38 · 3 records with a druggable one
Structures
23 records of P0AC41 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1NEK | Complex II (Succinate Dehydrogenase) From E. Coli with ubiqui bound | x-ray diffraction | A | — | — |
| 1NEK | Complex II (succinate dehydrogenase) from E. COLI with ubiquinone bound | x-ray diffraction | A | — | — |
| 1NEN | Complex II (Succinate Dehydrogenase) From E. Coli with Dinitrophenol-17 inhibitor co-crystallized… | x-ray diffraction | A | — | — |
| 1NEN | Complex II (succinate dehydrogenase) from E. COLI with dinitrophenol-17 inhibitor co-crystallized… | x-ray diffraction | A | — | — |
| 2WDQ | E. coli succinate:qui oxidoreductase (SQR) with carboxin bound | x-ray diffraction | A, E, I | — | — |
| 2WDQ | E. COLI SUCCINATE:QUINONE oxidoreductase (sqr) with carboxin bound | x-ray diffraction | A, E, I | — | — |
| 2WDR | E. coli succinate:qui oxidoreductase (SQR) with pentachlorophenol bound | x-ray diffraction | A, E, I | — | — |
| 2WDR | E. COLI SUCCINATE:QUINONE oxidoreductase (sqr) with pentachlorophenol bound | x-ray diffraction | A, E, I | — | — |
| 2WDV | E. coli succinate:qui oxidoreductase (SQR) with an empty qui - binding pocket | x-ray diffraction | A, E, I | — | — |
| 2WDV | E. COLI SUCCINATE:QUINONE oxidoreductase (sqr) with an empty quinone-binding pocket | x-ray diffraction | A, E, I | — | — |
| 2WP9 | Crystal structure of the E. coli succinate:qui oxidoreductase (SQR) SdhB His207Thr mutant | x-ray diffraction | A, E, I | — | — |
| 2WP9 | Crystal structure of the E. COLI SUCCINATE:QUINONE oxidoreductase (sqr) sdhb HIS207THR mutant | x-ray diffraction | A, E, I | — | — |
| 2WS3 | Crystal structure of the E. coli succinate:qui oxidoreductase (SQR) SdhD Tyr83Phe mutant | x-ray diffraction | A, E, I | — | — |
| 2WS3 | Crystal structure of the E. COLI SUCCINATE:QUINONE oxidoreductase (sqr) sdhd TYR83PHE mutant | x-ray diffraction | A, E, I | — | — |
| 2WU2 | Crystal structure of the E. coli succinate:qui oxidoreductase (SQR) SdhC His84Met mutant | x-ray diffraction | A, E, I | — | — |
| 2WU2 | Crystal structure of the E. COLI SUCCINATE:QUINONE oxidoreductase (sqr) sdhc HIS84MET mutant | x-ray diffraction | A, E, I | — | — |
| 2WU5 | Crystal structure of the E. coli succinate:qui oxidoreductase (SQR) SdhD His71Met mutant | x-ray diffraction | A, E, I | — | — |
| 2WU5 | Crystal structure of the E. COLI SUCCINATE:QUINONE oxidoreductase (sqr) sdhd HIS71MET mutant | x-ray diffraction | A, E, I | — | — |
| 6C12 | SDHA-SDHE complex | x-ray diffraction | B, A | FAD, NA | 18 (best 0.76) |
| 6C12 | Sdha-sdhe complex | x-ray diffraction | B, A | FAD, NA | — |
| 7JZ2 | Succinate: qui oxidoreductase SQR from E.coli K12 | electron microscopy | A, E, I | FAD, NA | 12 (best 0.80) |
| 7JZ2 | Succinate: quinone oxidoreductase sqr from E.COLI K12 | electron microscopy | A, E, I | FAD, NA | — |
| P0AC41 | AlphaFold monomer V2.0 prediction for succinate dehydrogenase flavoprotein subunit (P0AC41) | predicted | A | — | 8 (best 0.79) |
Ligands
Experiment against prediction
- 2WP9 chain A against the predicted model P0AC41: TM-score 1.00, RMSD 0.58 Å
- 2WP9 chain A against the predicted model P0AC41: TM-score 1.00, RMSD 0.58 Å
- 2WU5 chain A against the predicted model P0AC41: TM-score 1.00, RMSD 0.59 Å
- 2WU5 chain A against the predicted model P0AC41: TM-score 1.00, RMSD 0.59 Å
- 2WS3 chain A against the predicted model P0AC41: TM-score 1.00, RMSD 0.59 Å
- 2WS3 chain A against the predicted model P0AC41: TM-score 1.00, RMSD 0.59 Å
- 2WU2 chain A against the predicted model P0AC41: TM-score 1.00, RMSD 0.59 Å
- 2WU2 chain A against the predicted model P0AC41: TM-score 1.00, RMSD 0.59 Å
- 2WDQ chain A against the predicted model P0AC41: TM-score 1.00, RMSD 0.59 Å
- 2WDQ chain A against the predicted model P0AC41: TM-score 1.00, RMSD 0.59 Å
Elsewhere
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