UniProt P0AA27
Thioredoxin-1 (P0AA27)
Thioredoxin-1 (UniProt P0AA27): 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AA27
- Protein
- Thioredoxin-1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 6 · 1 record with a druggable one
Structures
11 records of P0AA27 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1T7P | T7 DNA polymerase complexed to DNA PRIMER/TEMPLATE,A nucleoside triphosphate, and its processivity… | x-ray diffraction | B | — | — |
| 1T7P | T7 DNA polymerase complexed to DNA PRIMER/TEMPLATE,A nucleoside triphosphate, and its processivity… | x-ray diffraction | B | — | — |
| 3DXB | Structure of the UHM domain of Puf60 fused to thioredoxin | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3DXB | Structure of the uhm domain of PUF60 fused to thioredoxin | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 5E4W | Crystal structure of cpSRP43 chromodomains 2 and 3 in complex with the Alb3 tail | x-ray diffraction | A, B | CA | 6 (best 0.75) |
| 5E4W | Crystal structure of CPSRP43 chromodomains 2 and 3 in complex with the ALB3 tail | x-ray diffraction | A, B | — | — |
| 5HR1 | Crystal structure of thioredoxin L107A mutant | x-ray diffraction | A, B, C, D, E, F, G | CU | — |
| 5HR1 | Crystal structure of thioredoxin L107A mutant | x-ray diffraction | A, B, C, D, E, F, G | — | — |
| 5IKN | Crystal Structure of the T7 Replisome in the Absence of DNA | x-ray diffraction | K, L, M | — | — |
| 5IKN | Crystal structure of the T7 replisome in the absence of DNA | x-ray diffraction | K, L, M | — | — |
| P0AA27 | AlphaFold monomer V2.0 prediction for thioredoxin 1 (P0AA27) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5HR1 chain C against the predicted model P0AA27: TM-score 0.99, RMSD 0.43 Å
- 5HR1 chain C against the predicted model P0AA27: TM-score 0.99, RMSD 0.43 Å
- 5HR1 chain G against the predicted model P0AA27: TM-score 0.99, RMSD 0.35 Å
- 5HR1 chain G against the predicted model P0AA27: TM-score 0.99, RMSD 0.35 Å
- 5HR1 chain A against the predicted model P0AA27: TM-score 0.98, RMSD 0.51 Å
- 5HR1 chain A against the predicted model P0AA27: TM-score 0.98, RMSD 0.51 Å
- 1T7P chain B against the predicted model P0AA27: TM-score 0.98, RMSD 0.55 Å
- 1T7P chain B against the predicted model P0AA27: TM-score 0.98, RMSD 0.55 Å
- 3DXB chain A against the predicted model P0AA27: TM-score 0.50, RMSD 1.02 Å
- 3DXB chain A against the predicted model P0AA27: TM-score 0.50, RMSD 1.02 Å
Elsewhere
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