UniProt P0A9C5
Glutamine synthetase (P0A9C5)
Glutamine synthetase (UniProt P0A9C5), EC 6.3.1.2: 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 56 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A9C5
- Protein
- Glutamine synthetase
- EC
- 6.3.1.2
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 56 · 4 records with a druggable one
Structures
4 records of P0A9C5 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7W85 | Structural of the filamentous Escherichia coli glutamine synthetase | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, U, V, W, X, Y | NI | 20 (best 0.81) |
| 8V1Y | Composite map of AMPylated GlnA bound to hinT | electron microscopy | A, B | AMP | 13 (best 0.65) |
| 8V22 | GlnA dodecamer with AMPylation | electron microscopy | C, D, F, H, I, J, L, A, B, G, E, K | MN | 20 (best 0.79) |
| P0A9C5 | AlphaFold monomer V2.0 prediction for glutamine synthetase (P0A9C5) | predicted | A | — | 3 (best 0.64) |
Ligands
Experiment against prediction
- 8V22 chain F against the predicted model P0A9C5: TM-score 1.00, RMSD 0.48 Å
- 8V22 chain C against the predicted model P0A9C5: TM-score 1.00, RMSD 0.49 Å
- 8V1Y chain A against the predicted model P0A9C5: TM-score 0.99, RMSD 1.12 Å
- 8V1Y chain B against the predicted model P0A9C5: TM-score 0.99, RMSD 1.09 Å
- 7W85 chain A against the predicted model P0A9C5: TM-score 0.99, RMSD 1.00 Å
Elsewhere
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