UniProt P0A962
L-asparaginase 1 (P0A962)
L-asparaginase 1 (UniProt P0A962), EC 3.5.1.1: 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A962
- Protein
- L-asparaginase 1
- EC
- 3.5.1.1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 20 · 1 record with a druggable one
Structures
11 records of P0A962 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2HIM | Crystal Structure and Allosteric Regulation of the Cytoplasmic Escherichia coli L-Asparaginase I | x-ray diffraction | A, B, C, D | — | — |
| 2HIM | Crystal structure and allosteric regulation of the cytoplasmic escherichia COLI L-asparaginase I | x-ray diffraction | A, B, C, D | — | — |
| 2P2D | Crystal Structure and Allosteric Regulation of the Cytoplasmic Escherichia coli L-Asparaginase I | x-ray diffraction | A, B, C, D | — | — |
| 2P2D | Crystal structure and allosteric regulation of the cytoplasmic escherichia COLI L-asparaginase I | x-ray diffraction | A, B, C, D | — | — |
| 2P2N | Crystal Structure and Allosteric Regulation of the Cytoplasmic Escherichia coli L-Asparaginase I | x-ray diffraction | A, B, C, D | — | — |
| 2P2N | Crystal structure and allosteric regulation of the cytoplasmic escherichia COLI L-asparaginase I | x-ray diffraction | A, B, C, D | — | — |
| 6NXC | ECAI(T162A) mutant in complex with citrate at pH 4 | x-ray diffraction | A, B, C, D | CL | — |
| 6NXC | ECAI(T162A) mutant in complex with citrate at pH 4 | x-ray diffraction | A, B, C, D | CL | — |
| 6NXD | Type I L-asparaginase from escherichia COLI in complex with citrate at pH 4 | x-ray diffraction | A, B, C, D | CL, ASN | 20 (best 0.83) |
| 6NXD | Type I L-asparaginase from escherichia COLI in complex with citrate at pH 4 | x-ray diffraction | A, B, C, D | CL | — |
| P0A962 | AlphaFold monomer V2.0 prediction for L-asparaginase 1 (P0A962) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6NXD chain C against the predicted model P0A962: TM-score 0.99, RMSD 0.67 Å
- 6NXD chain A against the predicted model P0A962: TM-score 0.99, RMSD 0.69 Å
- 6NXD chain C against the predicted model P0A962: TM-score 0.99, RMSD 0.67 Å
- 6NXD chain A against the predicted model P0A962: TM-score 0.99, RMSD 0.69 Å
- 6NXC chain C against the predicted model P0A962: TM-score 0.99, RMSD 0.71 Å
- 6NXC chain C against the predicted model P0A962: TM-score 0.99, RMSD 0.71 Å
- 6NXC chain A against the predicted model P0A962: TM-score 0.98, RMSD 0.75 Å
- 6NXC chain A against the predicted model P0A962: TM-score 0.98, RMSD 0.75 Å
- 2P2D chain B against the predicted model P0A962: TM-score 0.98, RMSD 0.94 Å
- 2P2D chain B against the predicted model P0A962: TM-score 0.98, RMSD 0.94 Å
Elsewhere
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