UniProt P0A7I0
Peptide chain release factor 1 (P0A7I0)
Peptide chain release factor 1 (UniProt P0A7I0): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A7I0
- Protein
- Peptide chain release factor 1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 10 · 2 records with a druggable one
Structures
9 records of P0A7I0 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2B3T | Structure of complex between E. coli translation termination factor RF1 and the PrmC… | x-ray diffraction | B | — | — |
| 2B3T | Structure of complex between E. COLI translation termination factor RF1 and the prmc… | x-ray diffraction | B | — | — |
| 5J4D | E. coli release factor 1 bound to the 70S ribosome in response to a pseudouridylated stop codon | x-ray diffraction | JA, OC | MG | 3 (best 0.88) |
| 6GWT | Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA… | electron microscopy | v | — | — |
| 6GXM | Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA… | electron microscopy | v | — | — |
| 6GXN | Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA… | electron microscopy | v | — | — |
| 6GXO | Cryo-EM structure of a rotated E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and… | electron microscopy | v | — | — |
| 8AKN | Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the terminating… | electron microscopy | W | — | 4 (best 0.88) |
| P0A7I0 | AlphaFold monomer V2.0 prediction for peptide chain release factor RF1 (P0A7I0) | predicted | A | — | 3 (best 0.49) |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 6GXM chain v against the predicted model P0A7I0: TM-score 0.98, RMSD 0.92 Å
- 6GWT chain v against the predicted model P0A7I0: TM-score 0.98, RMSD 0.96 Å
- 5J4D chain JA against the predicted model P0A7I0: TM-score 0.97, RMSD 1.09 Å
- 6GXO chain v against the predicted model P0A7I0: TM-score 0.96, RMSD 1.19 Å
- 8AKN chain W against the predicted model P0A7I0: TM-score 0.75, RMSD 3.13 Å
- 6GXN chain v against the predicted model P0A7I0: TM-score 0.74, RMSD 3.26 Å
- 2B3T chain B against the predicted model P0A7I0: TM-score 0.70, RMSD 3.46 Å
- 2B3T chain B against the predicted model P0A7I0: TM-score 0.70, RMSD 3.46 Å
Elsewhere
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