UniProt P0A7C2
LexA repressor (P0A7C2)
LexA repressor (UniProt P0A7C2), EC 3.4.21.88: 20 experimental structures and 1 predicted model on GenesisL1, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A7C2
- Protein
- LexA repressor
- EC
- 3.4.21.88
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 22 · 2 records with a druggable one
Structures
21 records of P0A7C2 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JHC | Lexa S119A C-terminal tryptic fragment | x-ray diffraction | A | — | — |
| 1JHC | Lexa S119A C-terminal tryptic fragment | x-ray diffraction | A | — | — |
| 1JHE | Lexa L89P Q92W E152A K156A mutant | x-ray diffraction | A, B | — | — |
| 1JHE | Lexa L89P Q92W E152A K156A mutant | x-ray diffraction | A, B | — | — |
| 1JHF | Lexa G85D mutant | x-ray diffraction | A, B | — | — |
| 1JHF | Lexa G85D mutant | x-ray diffraction | A, B | — | — |
| 1JHH | Lexa S119A mutant | x-ray diffraction | A, B | — | — |
| 1JHH | Lexa S119A mutant | x-ray diffraction | A, B | — | — |
| 1LEA | Solution structure of the lexa repressor DNA binding determined by 1H NMR spectroscopy | solution nmr | A | — | — |
| 1LEA | Solution structure of the lexa repressor DNA binding determined by 1H NMR spectroscopy | solution nmr | A | — | — |
| 1LEB | Solution structure of the lexa repressor DNA binding determined by 1H NMR spectroscopy | solution nmr | A | — | — |
| 1LEB | Solution structure of the lexa repressor DNA binding determined by 1H NMR spectroscopy | solution nmr | A | — | — |
| 3JSO | Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex | x-ray diffraction | A, B | — | — |
| 3JSO | Classic protein with a new twist: crystal structure of a lexa repressor DNA complex | x-ray diffraction | A, B | — | — |
| 3JSP | Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex | x-ray diffraction | A, B | — | — |
| 3JSP | Classic protein with a new twist: crystal structure of a lexa repressor DNA complex | x-ray diffraction | A, B | — | — |
| 3K3R | Unrefined crystal structure of a LexA-DNA complex | x-ray diffraction | E, F | — | — |
| 3K3R | Unrefined crystal structure of a lexa-DNA complex | x-ray diffraction | E, F | — | — |
| 7B5G | Crystal structure of E.coli LexA in complex with nanobody NbSOS3(Nb14527) | x-ray diffraction | A, C, E, G | — | 18 (best 0.56) |
| 8TRG | Structure of full-length LexA bound to a RecA filament | electron microscopy | I, J | — | 4 (best 0.85) |
| P0A7C2 | AlphaFold monomer V2.0 prediction for lexa repressor (P0A7C2) | predicted | A | — | — |
Experiment against prediction
- 1JHF chain B against the predicted model P0A7C2: TM-score 0.98, RMSD 0.57 Å
- 1JHF chain B against the predicted model P0A7C2: TM-score 0.98, RMSD 0.57 Å
- 1JHF chain A against the predicted model P0A7C2: TM-score 0.97, RMSD 0.90 Å
- 1JHF chain A against the predicted model P0A7C2: TM-score 0.97, RMSD 0.90 Å
- 1JHH chain A against the predicted model P0A7C2: TM-score 0.97, RMSD 0.97 Å
- 1JHH chain A against the predicted model P0A7C2: TM-score 0.97, RMSD 0.97 Å
- 7B5G chain C against the predicted model P0A7C2: TM-score 0.96, RMSD 1.22 Å
- 7B5G chain A against the predicted model P0A7C2: TM-score 0.96, RMSD 1.26 Å
- 7B5G chain G against the predicted model P0A7C2: TM-score 0.96, RMSD 1.19 Å
- 7B5G chain E against the predicted model P0A7C2: TM-score 0.96, RMSD 1.22 Å
Elsewhere
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