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UniProt P0A717

Ribose-phosphate pyrophosphokinase (P0A717)

Ribose-phosphate pyrophosphokinase (UniProt P0A717), EC 2.7.6.1: 6 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 53 pockets. Binding sites, druggability and experiment against prediction (TM-score)…

UniProt
P0A717
Protein
Ribose-phosphate pyrophosphokinase
EC
2.7.6.1
Experimental structures
6
Predicted models
1
Ligands
5
Pockets
53 · 4 records with a druggable one

Structures

7 records of P0A717 in the MolNFT archive: 6 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7XMUE.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5Pelectron microscopyA, D, B, E, F, CHSX, MG, PO4, ADP16 (best 0.78)
7XMUE.COLI phosphoribosylpyrophosphate (prpp) synthetase type a filament bound with ADP, pi and R5Pelectron microscopyA, D, B, E, F, CHSX, MG, PO4, ADP—
7XMVE.coli phosphoribosylpyrophosphate (PRPP) synthetase type A(AMP/ADP) filament bound with ADP, AMP…electron microscopyA, E, C, D, B, FHSX, MG, ADP, AMP20 (best 0.78)
7XMVE.COLI phosphoribosylpyrophosphate (prpp) synthetase type A(AMP/ADP) filament bound with ADP, AMP…electron microscopyA, E, C, D, B, FHSX, MG, ADP, AMP—
7XN3E.coli phosphoribosylpyrophosphate (PRPP) synthetase type B filament bound with Pielectron microscopyA, B, F, E, C, DPO414 (best 0.83)
7XN3E.COLI phosphoribosylpyrophosphate (prpp) synthetase type B filament bound with pielectron microscopyA, B, F, E, C, DPO4—
P0A717AlphaFold monomer V2.0 prediction for ribose-phosphate pyrophosphokinase (P0A717)predictedA—3 (best 0.57)

Ligands

  • ADP · Adenosine-5'-diphosphate · in 4 records
  • HSX · 5-O-phosphono-alpha-D-ribofuranose · in 4 records
  • MG · Magnesium ion · in 4 records
  • PO4 · Phosphate ion · in 4 records
  • AMP · Adenosine monophosphate · in 2 records

Experiment against prediction

Elsewhere

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