UniProt P0A705
Translation initiation factor IF-2 (P0A705)
Translation initiation factor IF-2 (UniProt P0A705): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A705
- Protein
- Translation initiation factor IF-2
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 6 · 2 records with a druggable one
Structures
11 records of P0A705 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ND9 | Solution Structure of the N-terminal Subdomain of Translation Initiation Factor IF2 | solution nmr | A | — | — |
| 1ND9 | Solution structure of the N-terminal subdomain of translation initiation factor IF2 | solution nmr | A | — | — |
| 1ZO1 | IF2, IF1, and tRNA fitted to cryo-EM data OF E. COLI 70S initiation complex | electron microscopy | I | — | — |
| 1ZO1 | IF2, IF1, and tRNA fitted to cryo-EM data of E. COLI 70S initiation complex | electron microscopy | I | — | — |
| 3JCJ | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association | electron microscopy | f | — | — |
| 3JCN | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association… | electron microscopy | b | — | — |
| 5ME0 | Structure of the 30S Pre-Initiation Complex 1 (30S IC-1) Stalled by GE81112 | electron microscopy | W | FME | — |
| 5ME0 | Structure of the 30S pre-initiation complex 1 (30S ic-1) stalled by GE81112 | electron microscopy | W | FME | — |
| 5ME1 | Structure of the 30S Pre-Initiation Complex 2 (30S IC-2) Stalled by GE81112 | electron microscopy | W | FME | 1 (best 0.78) |
| 5ME1 | Structure of the 30S pre-initiation complex 2 (30S ic-2) stalled by GE81112 | electron microscopy | W | FME | — |
| P0A705 | AlphaFold monomer V2.0 prediction for translation initiation factor if-2 (P0A705) | predicted | A | — | 5 (best 0.55) |
Ligands
- FME · N-formylmethionine · in 4 records
Experiment against prediction
- 5ME0 chain W against the predicted model P0A705: TM-score 0.90, RMSD 2.69 Å
- 5ME0 chain W against the predicted model P0A705: TM-score 0.90, RMSD 2.69 Å
- 5ME1 chain W against the predicted model P0A705: TM-score 0.89, RMSD 2.83 Å
- 5ME1 chain W against the predicted model P0A705: TM-score 0.89, RMSD 2.83 Å
- 3JCJ chain f against the predicted model P0A705: TM-score 0.88, RMSD 2.95 Å
- 3JCN chain b against the predicted model P0A705: TM-score 0.88, RMSD 2.95 Å
- 1ZO1 chain I against the predicted model P0A705: TM-score 0.57, RMSD 5.71 Å
- 1ZO1 chain I against the predicted model P0A705: TM-score 0.57, RMSD 5.71 Å
- 1ND9 chain A against the predicted model P0A705: TM-score 0.43, RMSD 2.96 Å
- 1ND9 chain A against the predicted model P0A705: TM-score 0.43, RMSD 2.96 Å
Elsewhere
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