UniProt P0A6X7
Integration Host Factor Alpha-subunit (P0A6X7)
Integration Host Factor Alpha-subunit (UniProt P0A6X7): 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 68 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A6X7
- Protein
- Integration Host Factor Alpha-subunit
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 68 · 14 records with a druggable one
Structures
15 records of P0A6X7 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1IHF | Integration host FACTOR/DNA complex | x-ray diffraction | A | CD | 4 (best 0.81) |
| 1IHF | Integration host FACTOR/DNA complex | x-ray diffraction | A | CD | 4 (best 0.81) |
| 1OUZ | Crystal structure of a mutant IHF (BetaE44A) complexed with a variant H' Site (T44A) | x-ray diffraction | A | — | 5 (best 0.80) |
| 1OUZ | Crystal structure of a mutant ihf (BETAE44A) complexed with a variant H' site (T44A) | x-ray diffraction | A | — | 5 (best 0.80) |
| 1OWF | Crystal structure of a mutant IHF (BetaE44A) complexed with the native H' Site | x-ray diffraction | A | — | 5 (best 0.79) |
| 1OWF | Crystal structure of a mutant ihf (BETAE44A) complexed with the native H' site | x-ray diffraction | A | — | 5 (best 0.79) |
| 1OWG | Crystal structure of WT IHF complexed with an altered H' site (T44A) | x-ray diffraction | A | — | 5 (best 0.80) |
| 1OWG | Crystal structure of wt ihf complexed with an altered H' site (T44A) | x-ray diffraction | A | — | 5 (best 0.80) |
| 2HT0 | IHF bound to doubly nicked DNA | x-ray diffraction | A | — | 5 (best 0.78) |
| 2HT0 | Ihf bound to doubly nicked DNA | x-ray diffraction | A | — | 5 (best 0.78) |
| 2IIE | single chain Integration Host Factor protein (scIHF2) in complex with DNA | x-ray diffraction | A | MN | 5 (best 0.78) |
| 2IIE | Single chain integration host factor protein (SCIHF2) in complex with DNA | x-ray diffraction | A | MN | 5 (best 0.78) |
| 2IIF | single chain Integration Host Factor mutant protein (scIHF2-K45aE) in complex with DNA | x-ray diffraction | A | MN | 5 (best 0.78) |
| 2IIF | Single chain integration host factor mutant protein (SCIHF2-K45AE) in complex with DNA | x-ray diffraction | A | MN | 5 (best 0.78) |
| P0A6X7 | AlphaFold monomer V2.0 prediction for integration host factor subunit alpha (P0A6X7) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2IIF chain A against the predicted model P0A6Y1: TM-score 0.45, RMSD 0.74 Å
- 2IIF chain A against the predicted model P0A6Y1: TM-score 0.45, RMSD 0.74 Å
- 2IIE chain A against the predicted model P0A6Y1: TM-score 0.45, RMSD 0.78 Å
- 2IIE chain A against the predicted model P0A6Y1: TM-score 0.45, RMSD 0.78 Å
- 1IHF chain A against the predicted model P0A6X7: TM-score 0.96, RMSD 1.16 Å
- 1IHF chain A against the predicted model P0A6X7: TM-score 0.96, RMSD 1.16 Å
- 1OWF chain A against the predicted model P0A6X7: TM-score 0.96, RMSD 1.18 Å
- 1OWF chain A against the predicted model P0A6X7: TM-score 0.96, RMSD 1.18 Å
- 2HT0 chain A against the predicted model P0A6X7: TM-score 0.96, RMSD 1.19 Å
- 2HT0 chain A against the predicted model P0A6X7: TM-score 0.96, RMSD 1.19 Å
Elsewhere
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