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UniProt P08669

Glycoprotein G2 (P08669)

Glycoprotein G2 (UniProt P08669): 22 experimental structures on GenesisL1, 6 ligands bound, 230 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P08669
Protein
Glycoprotein G2
Experimental structures
22
Predicted models
0
Ligands
6
Pockets
230 · 14 records with a druggable one

Structures

22 records of P08669 in the MolNFT archive: 22 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5FT2Sub-tomogram averaging of Lassa virus glycoprotein spike from virus- like particles at pH 5electron microscopyBNAG1 (best 0.30)
5FT2Sub-tomogram averaging of lassa virus glycoprotein spike from virus- like particles at pH 5electron microscopyB——
5VK2Structural basis for antibody-mediated neutralization of Lassa virusx-ray diffractionA, a, B, b, C, cNAG, BMA, MAN, FUC16 (best 0.83)
5VK2Structural basis for antibody-mediated neutralization of lassa virusx-ray diffractionA, a, B, b, C, cNAG, BMA, MAN, FUC—
6P95Structure of lassa virus glycoprotein in complex with Fab 25.6Ax-ray diffractionA, B, C, a, b, cNAG, BMA, MAN, FUC—
7PUYStructure of the membrane soluble spike complex from the Lassa virus in a C3-symmetric mapelectron microscopya, b, c, A, B, CNAG, XYS, BDP15 (best 0.85)
7PUYStructure of the membrane soluble spike complex from the lassa virus in a C3-symmetric MAPelectron microscopya, b, c, A, B, CNAG, XYS, BDP—
7PVDStructure of the membrane soluble spike complex from the lassa virus in a C1-symmetric MAP focused…electron microscopya, b, c, A, B, CNAG, XYS, BDP—
7S8HStructure of lassa virus glycoprotein bound to Fab 18.5C and Fab 36.1Fx-ray diffractionA, aNAG, BMA, MAN, FUC—
7TYVStructure of Lassa Virus glycoprotein (Josiah) bound to Fab 25.10Celectron microscopyA, B, C, a, b, cNAG, BMA, MAN10 (best 0.78)
7TYVStructure of lassa virus glycoprotein (josiah) bound to Fab 25.10Celectron microscopyA, B, C, a, b, cNAG, BMA, MAN—
7UOTNative Lassa glycoprotein in complex with neutralizing antibodies 8.9F and 37.2Delectron microscopyA, a, B, b, C, cNAG, BMA, FUC, MAN18 (best 0.86)
7UOVNative Lassa glycoprotein in complex with neutralizing antibodies 12.1F and 37.2Delectron microscopyA, a, B, b, C, cNAG, BMA, FUC, MAN19 (best 0.85)
8EJDStructure of lineage IV Lassa virus glycoprotein complex (strain Josiah)electron microscopyC, c, A, a, B, bNAG, BMA, FUC, MAN19 (best 0.87)
8EJHLassa virus glycoprotein complex (Josiah) bound to 12.1F Fabelectron microscopyC, B, c, A, b, aNAG, BMA, MAN20 (best 0.85)
8EJILassa virus glycoprotein complex (Josiah) bound to 19.7E Fabelectron microscopyA, a, B, b, C, cNAG, BMA, MAN18 (best 0.78)
8TYCLassa GPC (strain Josiah) bound to rabbit polyclonal base-targeting antibody Base-1electron microscopyA, B, C, a, b, cNAG, BMA, FUC, MAN19 (best 0.81)
8TYELassa GPC (strain Josiah) bound to rabbit polyclonal fusion-peptide-targeting antibody FP-1electron microscopyC, A, B, c, a, bNAG, FUC, BMA, MAN17 (best 0.82)
8VCVLineage IV Lassa virus glycoprotein (Josiah) in complex with rabbit polyclonal antibody (GPC-C…electron microscopyA, B, C, a, b, cNAG, FUC, BMA, MAN13 (best 0.85)
8VE8Lineage IV Lassa virus glycoprotein (Josiah) in complex with rabbit polyclonal antibody (GP1-A…electron microscopyA, B, C, a, b, cNAG, FUC, BMA, MAN15 (best 0.85)
9CJ7Lineage IV Lassa virus glycoprotein (Josiah) in complex with monoclonal antibody 8.9Felectron microscopyC, A, B, c, a, bNAG, FUC, BMA, MAN16 (best 0.81)
9CK8Lineage IV Lassa virus glycoprotein (Josiah) in complex with polyclonal antibody (GPC-A epitope)…electron microscopyC, A, B, a, b, cNAG, FUC, BMA, MAN14 (best 0.82)

Ligands

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 21 records
  • BMA · beta-D-mannopyranose · in 17 records
  • MAN · alpha-D-mannopyranose · in 17 records
  • FUC · alpha-L-fucopyranose · in 13 records
  • BDP · beta-D-glucopyranuronic acid · in 3 records
  • XYS · alpha-D-xylopyranose · in 3 records

Elsewhere

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