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UniProt P08559

P08559

P08559 (UniProt P08559): 17 experimental structures on GenesisL1, 3 ligands bound. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P08559
Experimental structures
17
Predicted models
0
Ligands
3

Structures

17 records of P08559 in the MolNFT archive: 17 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1NI4Human pyruvate dehydrogenasex-ray diffractionA, C——
1NI4Human pyruvate dehydrogenasex-ray diffractionA, C——
2OZLHuman pyruvate dehydrogenase S264E variantx-ray diffractionA, C——
2OZLHuman pyruvate dehydrogenase S264E variantx-ray diffractionA, C——
3EXECrystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase…x-ray diffractionA, C, E, G——
3EXECrystal structure of the pyruvate dehydrogenase (E1P) component of human pyruvate dehydrogenase…x-ray diffractionA, C, E, G——
3EXFCrystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase…x-ray diffractionA, C, E, G——
3EXFCrystal structure of the pyruvate dehydrogenase (E1P) component of human pyruvate dehydrogenase…x-ray diffractionA, C, E, G——
3EXGCrystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase…x-ray diffractionA, C, E, G, I, K, M, O, Q, S, U, W, Y, 1, 3, 5——
3EXGCrystal structure of the pyruvate dehydrogenase (E1P) component of human pyruvate dehydrogenase…x-ray diffractionA, C, E, G, I, K, M, O, Q, S, U, W, Y, 1, 3, 5——
3EXHCrystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase…x-ray diffractionA, C, E, G——
3EXHCrystal structure of the pyruvate dehydrogenase (E1P) component of human pyruvate dehydrogenase…x-ray diffractionA, C, E, G——
3EXICrystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase…x-ray diffractionA——
3EXICrystal structure of the pyruvate dehydrogenase (E1P) component of human pyruvate dehydrogenase…x-ray diffractionA——
6CERHuman pyruvate dehydrogenase complex E1 component V138M mutationx-ray diffractionA, C, E, GTPP, MG—
6CFOHuman pyruvate dehydrogenase E1 component complex with covalent tdp adduct acetyl phosphinatex-ray diffractionA, CA5X, MG—
P08559AlphaFold monomer V2.0 prediction for pyruvate dehydrogenase E1 component subunit alpha, somatic…———

Ligands

  • MG · Magnesium ion · in 2 records
  • A5X · 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(1S)-1-hydroxy-1-[(R)-hydroxy(oxo)-lambda~5~-phosphanyl]ethyl}-5-(2-{[(S)-hydroxy(phosphonooxy) phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium · in 1 record
  • TPP · Thiamine diphosphate · in 1 record

Elsewhere

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