UniProt P08394
RecBCD enzyme subunit RecB (P08394)
RecBCD enzyme subunit RecB (UniProt P08394), EC 3.1.11.5: 27 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 154 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P08394
- Protein
- RecBCD enzyme subunit RecB
- EC
- 3.1.11.5
- Experimental structures
- 27
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 154 · 12 records with a druggable one
Structures
28 records of P08394 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1W36 | RECBCD:DNA complex | x-ray diffraction | B, E | — | — |
| 3K70 | Crystal structure of the complete initiation complex of RecBCD | x-ray diffraction | B, E | — | — |
| 3K70 | Crystal structure of the complete initiation complex of recbcd | x-ray diffraction | B, E | — | — |
| 5LD2 | Cryo-EM structure of RecBCD+DNA complex revealing activated nuclease domain | electron microscopy | B | ANP, MG | — |
| 5LD2 | Cryo-EM structure of RECBCD+DNA complex revealing activated nuclease domain | electron microscopy | B | ANP, MG | — |
| 5MBV | Cryo-EM structure of Lambda Phage protein GamS bound to RecBCD. | electron microscopy | B | — | 15 (best 0.83) |
| 5MBV | Cryo-EM structure of lambda phage protein gams bound to recbcd. | electron microscopy | B | — | — |
| 6SJE | Cryo-EM structure of the RecBCD Chi partially-recognised complex | electron microscopy | B | — | 14 (best 0.85) |
| 6SJE | Cryo-EM structure of the recbcd chi partially-recognised complex | electron microscopy | B | — | — |
| 6SJF | Cryo-EM structure of the RecBCD Chi unrecognised complex | electron microscopy | B | — | 13 (best 0.80) |
| 6SJF | Cryo-EM structure of the recbcd chi unrecognised complex | electron microscopy | B | — | — |
| 6SJG | Cryo-EM structure of the RecBCD no Chi negative control complex | electron microscopy | B | — | 11 (best 0.83) |
| 6SJG | Cryo-EM structure of the recbcd no chi negative control complex | electron microscopy | B | — | — |
| 6T2U | Cryo-EM structure of the RecBCD in complex with Chi-minus2 substrate | electron microscopy | B | — | 11 (best 0.82) |
| 6T2U | Cryo-EM structure of the recbcd in complex with chi-MINUS2 substrate | electron microscopy | B | — | — |
| 6T2V | Cryo-EM structure of the RecBCD in complex with Chi-plus2 substrate | electron microscopy | B | — | 13 (best 0.82) |
| 6T2V | Cryo-EM structure of the recbcd in complex with chi-PLUS2 substrate | electron microscopy | B | — | — |
| 7MR0 | Cryo-EM structure of RecBCD with docked RecBNuc and flexible RecD | electron microscopy | B | — | 15 (best 0.81) |
| 7MR0 | Cryo-EM structure of recbcd with docked recbnuc and flexible recd | electron microscopy | B | — | — |
| 7MR1 | Cryo-EM structure of RecBCD with undocked RecBNuc and flexible RecD C-terminus | electron microscopy | B | — | 10 (best 0.83) |
| 7MR1 | Cryo-EM structure of recbcd with undocked recbnuc and flexible recd C- terminus | electron microscopy | B | — | — |
| 7MR2 | Cryo-EM structure of RecBCD with undocked RecBNuc and flexible RecD | electron microscopy | B | — | 13 (best 0.81) |
| 7MR2 | Cryo-EM structure of recbcd with undocked recbnuc and flexible recd | electron microscopy | B | — | — |
| 7MR3 | Cryo-EM structure of RecBCD-DNA complex with docked RecBNuc and stabilized RecD | electron microscopy | B | — | 13 (best 0.79) |
| 7MR3 | Cryo-EM structure of recbcd-DNA complex with docked recbnuc and stabilized recd | electron microscopy | B | — | — |
| 7MR4 | Cryo-EM structure of RecBCD-DNA complex with undocked RecBNuc and flexible RecD | electron microscopy | B | — | 14 (best 0.84) |
| 7MR4 | Cryo-EM structure of recbcd-DNA complex with undocked recbnuc and flexible recd | electron microscopy | B | — | — |
| P08394 | AlphaFold monomer V2.0 prediction for recbcd enzyme subunit recb (P08394) | predicted | A | — | 12 (best 0.79) |
Ligands
Experiment against prediction
- 7MR4 chain B against the predicted model P08394: TM-score 0.95, RMSD 2.22 Å
- 7MR4 chain B against the predicted model P08394: TM-score 0.95, RMSD 2.22 Å
- 7MR2 chain B against the predicted model P08394: TM-score 0.92, RMSD 3.05 Å
- 7MR2 chain B against the predicted model P08394: TM-score 0.92, RMSD 3.05 Å
- 7MR1 chain B against the predicted model P08394: TM-score 0.91, RMSD 3.27 Å
- 7MR1 chain B against the predicted model P08394: TM-score 0.91, RMSD 3.27 Å
- 3K70 chain B against the predicted model P08394: TM-score 0.85, RMSD 4.87 Å
- 3K70 chain B against the predicted model P08394: TM-score 0.85, RMSD 4.87 Å
- 1W36 chain B against the predicted model P08394: TM-score 0.85, RMSD 4.85 Å
- 5MBV chain B against the predicted model P08394: TM-score 0.84, RMSD 5.13 Å
Elsewhere
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