UniProt P07948
Tyrosine-protein kinase Lyn (P07948)
Tyrosine-protein kinase Lyn (UniProt P07948), EC 2.7.10.2: 11 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P07948
- Protein
- Tyrosine-protein kinase Lyn
- EC
- 2.7.10.2
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 1 · 1 record with a druggable one
Structures
12 records of P07948 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1W1F | SH3 domain of human lyn tyrosine kinase | solution nmr | A | — | — |
| 1W1F | SH3 domain of human lyn tyrosine kinase | solution nmr | A | — | — |
| 1WA7 | SH3 domain of human lyn tyrosine kinase in complex with a herpesviral ligand | solution nmr | A | — | — |
| 1WA7 | SH3 domain of human lyn tyrosine kinase in complex with a herpesviral ligand | solution nmr | A | — | — |
| 3A4O | Lyn kinase domain | x-ray diffraction | X | — | — |
| 3A4O | Lyn kinase domain | x-ray diffraction | X | — | — |
| 5XY1 | Crystal structure of Lyn kinase domain in complex with… | x-ray diffraction | A | 8H0 | 1 (best 0.66) |
| 5XY1 | Crystal structure of lyn kinase domain in complex with N-(1H-indazol… | x-ray diffraction | A | 8H0 | — |
| 6NMW | Crystal structure of the human Lyn SH3 domain | x-ray diffraction | A | — | — |
| 6NMW | Crystal structure of the human lyn SH3 domain | x-ray diffraction | A | — | — |
| 8WFF | The Crystal Structure of LYN from Biortus. | x-ray diffraction | A | CL | — |
| P07948 | AlphaFold monomer V2.0 prediction for tyrosine-protein kinase lyn (P07948) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5XY1 chain A against the predicted model P07948: TM-score 0.94, RMSD 1.69 Å
- 5XY1 chain A against the predicted model P07948: TM-score 0.94, RMSD 1.69 Å
- 3A4O chain X against the predicted model P07948: TM-score 0.92, RMSD 2.13 Å
- 3A4O chain X against the predicted model P07948: TM-score 0.92, RMSD 2.13 Å
- 8WFF chain A against the predicted model P07948: TM-score 0.92, RMSD 1.17 Å
- 6NMW chain A against the predicted model P07948: TM-score 0.91, RMSD 1.29 Å
- 6NMW chain A against the predicted model P07948: TM-score 0.91, RMSD 1.29 Å
- 1WA7 chain A against the predicted model P07948: TM-score 0.89, RMSD 1.09 Å
- 1WA7 chain A against the predicted model P07948: TM-score 0.89, RMSD 1.09 Å
- 1W1F chain A against the predicted model P07948: TM-score 0.86, RMSD 1.34 Å
Elsewhere
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