UniProt P07607
Thymidylate synthase (P07607)
Thymidylate synthase (UniProt P07607), EC 2.1.1.45: 17 experimental structures on GenesisL1, 5 ligands bound, 9 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P07607
- Protein
- Thymidylate synthase
- EC
- 2.1.1.45
- Experimental structures
- 17
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 9 · 1 record with a druggable one
Structures
17 records of P07607 in the MolNFT archive: 17 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3IHI | Crystal structure of mouse thymidylate synthase | x-ray diffraction | A, B | — | — |
| 3IHI | Crystal structure of mouse thymidylate synthase | x-ray diffraction | A, B | — | — |
| 4E5O | Crystal structure of mouse thymidylate synthase in complex with dUMP | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4E5O | Crystal structure of mouse thymidylate synthase in complex with dump | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4EB4 | Crystal structure of mouse thymidylate synthase in ternary complex with dUMP and Tomudex | x-ray diffraction | A, B, C, D | — | — |
| 4EB4 | Crystal structure of mouse thymidylate synthase in ternary complex with dump and tomudex | x-ray diffraction | A, B, C, D | — | — |
| 4EIN | Crystal structure of mouse thymidylate synthase in binary complex with a substrate analogue and… | x-ray diffraction | A, B | — | — |
| 4EIN | Crystal structure of mouse thymidylate synthase in binary complex with a substrate analogue and… | x-ray diffraction | A, B | — | — |
| 4EZ8 | Crystal structure of mouse thymidylate sythase in ternary complex with… | x-ray diffraction | A | — | — |
| 4EZ8 | Crystal structure of mouse thymidylate sythase in ternary complex with… | x-ray diffraction | A | — | — |
| 6F6Z | Mouse thymidylate synthase cocrystallized with N(4)OHDCMP and soaked in methylenetetrahydrofolate | x-ray diffraction | A, B | NOH | — |
| 6GKO | Mouse thymidylate synthase cocrystallized with dump and soaked in phenolphthalein | x-ray diffraction | A, B | UMP, FGT | — |
| 6GYJ | Mouse thymidylate synthase crystal soaked in phenolphthalein | x-ray diffraction | A, B | SO4, FGT | — |
| 6GYJ | Mouse thymidylate synthase crystal soaked in phenolphthalein | x-ray diffraction | A, B | SO4, FGT | — |
| 6Y08 | Mouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole | x-ray diffraction | A, B | UMP, 08D | 9 (best 0.68) |
| 6Y08 | Mouse thymidylate synthase cocrystallized with dump and soaked in sulfamethoxazole | x-ray diffraction | A, B | UMP, 08D | — |
| P07607 | AlphaFold monomer V2.0 prediction for thymidylate synthase (P07607) | — | — | — |
Ligands
Elsewhere
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