UniProt P07478
Trypsin-2 (P07478)
Trypsin-2 (UniProt P07478), EC 3.4.21.4: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P07478
- Protein
- Trypsin-2
- EC
- 3.4.21.4
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
3 records of P07478 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7Z9F | Human anionic trypsin after autoproteolysis at Arg122 | x-ray diffraction | X, A, Y, B | CA | 3 (best 0.79) |
| 7Z9F | Human anionic trypsin after autoproteolysis at ARG122 | x-ray diffraction | X, A, Y, B | CA | — |
| P07478 | AlphaFold monomer V2.0 prediction for trypsin-2 (P07478) | predicted | A | — | — |
Ligands
- CA · Calcium ion · in 2 records
Experiment against prediction
- 7Z9F chain B against the predicted model P07478: TM-score 1.00, RMSD 0.27 Å
- 7Z9F chain Y against the predicted model P07478: TM-score 1.00, RMSD 0.28 Å
- 7Z9F chain Y against the predicted model P07478: TM-score 1.00, RMSD 0.28 Å
- 7Z9F chain X against the predicted model P07478: TM-score 0.98, RMSD 0.86 Å
- 7Z9F chain X against the predicted model P07478: TM-score 0.98, RMSD 0.86 Å
- 7Z9F chain A against the predicted model P07478: TM-score 0.98, RMSD 0.86 Å
Elsewhere
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