UniProt P07358
Complement component C8 beta chain (P07358)
Complement component C8 beta chain (UniProt P07358): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P07358
- Protein
- Complement component C8 beta chain
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 11 · 2 records with a druggable one
Structures
9 records of P07358 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3OJY | Crystal Structure of Human Complement Component C8 | x-ray diffraction | B | — | — |
| 3OJY | Crystal structure of human complement component C8 | x-ray diffraction | B | — | — |
| 6H03 | Open conformation of the membrane attack complex | electron microscopy | C | NAG | — |
| 6H04 | Closed conformation of the Membrane Attack Complex | electron microscopy | C | NAG | — |
| 6H04 | Closed conformation of the membrane attack complex | electron microscopy | C | NAG | — |
| 7NYC | Cryoem structure of 3C9-smac | electron microscopy | D | NAG, BMA, CA | — |
| 8B0G | 2C9, C5b9-CD59 structure | electron microscopy | D | NAG | 5 (best 0.86) |
| 8B0H | 2C9, C5b9-CD59 cryoEM structure | electron microscopy | D | — | 6 (best 0.85) |
| P07358 | AlphaFold monomer V2.0 prediction for complement component C8 beta chain (P07358) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3OJY chain B against the predicted model P07358: TM-score 0.98, RMSD 1.15 Å
- 3OJY chain B against the predicted model P07358: TM-score 0.98, RMSD 1.15 Å
- 7NYC chain D against the predicted model P07358: TM-score 0.81, RMSD 2.72 Å
- 8B0H chain D against the predicted model P07358: TM-score 0.79, RMSD 2.45 Å
- 8B0G chain D against the predicted model P07358: TM-score 0.78, RMSD 2.49 Å
- 6H03 chain C against the predicted model P07358: TM-score 0.74, RMSD 2.46 Å
- 6H04 chain C against the predicted model P07358: TM-score 0.72, RMSD 2.80 Å
- 6H04 chain C against the predicted model P07358: TM-score 0.72, RMSD 2.80 Å
Elsewhere
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