UniProt P07251
ATP synthase subunit alpha (P07251)
ATP synthase subunit alpha (UniProt P07251): 94 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 513 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P07251
- Protein
- ATP synthase subunit alpha
- Experimental structures
- 94
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 513 · 37 records with a druggable one
Structures
95 records of P07251 in the MolNFT archive: 94 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2HLD | Crystal structure of yeast mitochondrial F1-ATPase | x-ray diffraction | A, B, C, J, K, L, S, T, U | — | — |
| 2HLD | Crystal structure of yeast mitochondrial F1-ATPase | x-ray diffraction | A, B, C, J, K, L, S, T, U | — | — |
| 2WPD | The Mg.ADP inhibited state of the yeast F1c10 ATP synthase | x-ray diffraction | A, B, C | — | — |
| 2WPD | The MG.ADP inhibited state of the yeast F1C10 ATP synthase | x-ray diffraction | A, B, C | — | — |
| 2XOK | Refined structure of yeast F1c10 ATPase complex to 3 A resolution | x-ray diffraction | A, B, C | — | — |
| 2XOK | Refined structure of yeast F1C10 ATPase complex to 3 a resolution | x-ray diffraction | A, B, C | — | — |
| 3FKS | Yeast F1 ATPase in the absence of bound nucleotides | x-ray diffraction | A, B, C, J, K, L, S, T, U | — | — |
| 3FKS | Yeast F1 ATPase in the absence of bound nucleotides | x-ray diffraction | A, B, C, J, K, L, S, T, U | — | — |
| 3OE7 | Structure of four mutant forms of yeast f1 ATPase: gamma-I270T | x-ray diffraction | A, B, C, J, K, L, S, T, U | — | — |
| 3OE7 | Structure of four mutant forms of yeast F1 ATPase: gamma-I270T | x-ray diffraction | A, B, C, J, K, L, S, T, U | — | — |
| 3OEE | Structure of four mutant forms of yeast F1 ATPase: alpha-F405S | x-ray diffraction | A, B, C, J, K, L, S, T, U | — | — |
| 3OEE | Structure of four mutant forms of yeast F1 ATPase: alpha-F405S | x-ray diffraction | A, B, C, J, K, L, S, T, U | — | — |
| 3OEH | Structure of four mutant forms of yeast F1 ATPase: beta-V279F | x-ray diffraction | A, B, C, J, K, L, S, T, U | — | — |
| 3OEH | Structure of four mutant forms of yeast F1 ATPase: beta-V279F | x-ray diffraction | A, B, C, J, K, L, S, T, U | — | — |
| 3OFN | Structure of four mutant forms of yeast F1 ATPase: alpha-N67I | x-ray diffraction | A, B, C, J, K, L, S, T, U | — | — |
| 3OFN | Structure of four mutant forms of yeast F1 ATPase: alpha-N67I | x-ray diffraction | A, B, C, J, K, L, S, T, U | — | — |
| 3ZIA | The structure of F1-ATPase from Saccharomyces cerevisiae inhibited by its regulatory protein IF1 | x-ray diffraction | A, B, C, K, L, M | — | — |
| 3ZIA | The structure of F1-ATPase from saccharomyces cerevisiae inhibited by its regulatory protein IF1 | x-ray diffraction | A, B, C, K, L, M | — | — |
| 3ZRY | Rotor architecture in the F(1)-c(10)-ring complex of the yeast F-ATP synthase | x-ray diffraction | A, B, C | — | — |
| 3ZRY | Rotor architecture in the F(1)-C(10)-ring complex of the yeast F-ATP synthase | x-ray diffraction | A, B, C | — | — |
| 4B2Q | Model of the yeast F1Fo-ATP synthase dimer based on subtomogram average | electron microscopy | A, B, C, a, b, c | — | — |
| 4B2Q | Model of the yeast F1FO-ATP synthase dimer based on subtomogram average | electron microscopy | A, B, C, a, b, c | — | — |
| 6B8H | Mosaic model of yeast mitochondrial ATP synthase monomer | electron microscopy | K, B, C, n, W, X | ANP, MG | 19 (best 0.89) |
| 6B8H | Mosaic model of yeast mitochondrial ATP synthase monomer | electron microscopy | K, B, C, n, W, X | ANP, MG | — |
| 6CP3 | Monomer yeast ATP synthase (F1Fo) reconstituted in nanodisc with inhibitor of oligomycin bound. | electron microscopy | A, B, C | ATP, ADP | 17 (best 0.85) |
| 6CP3 | Monomer yeast ATP synthase (F1FO) reconstituted in nanodisc with inhibitor of oligomycin bound. | electron microscopy | A, B, C | ATP, ADP | — |
| 6CP6 | Monomer yeast ATP synthase (F1Fo) reconstituted in nanodisc. | electron microscopy | A, B, C | ATP, ADP | 16 (best 0.85) |
| 6CP6 | Monomer yeast ATP synthase (F1FO) reconstituted in nanodisc. | electron microscopy | A, B, C | ATP, ADP | — |
| 7TJT | Yeast ATP synthase F1 region State 1-3catalytic beta_tight open without exogenous ATP | electron microscopy | A, B, C | ATP, MG, PO4 | 20 (best 0.88) |
| 7TJU | Yeast ATP synthase F1 region State 1-3binding beta_tight open without exogenous ATP | electron microscopy | A, B, C | ATP, MG, PO4 | 19 (best 0.87) |
| 7TJU | Yeast ATP synthase F1 region state 1-3BINDING BETA_TIGHT open without exogenous ATP | electron microscopy | A, B, C | ATP, MG | — |
| 7TJV | Yeast ATP synthase F1 region State 1catalytic(a) with 10 mM ATP | electron microscopy | A, B, C | ATP, MG, ADP | 20 (best 0.87) |
| 7TJW | Yeast ATP synthase F1 region State 1catalytic(e-h) with 10 mM ATP | electron microscopy | A, B, C | ATP, MG | 19 (best 0.87) |
| 7TJW | Yeast ATP synthase F1 region state 1CATALYTIC(E-H) with 10 mm ATP | electron microscopy | A, B, C | ATP, MG | — |
| 7TJX | Yeast ATP synthase F1 region State 1binding(a-d) with 10 mM ATP | electron microscopy | A, B, C | ATP, MG, ADP, PO4 | 18 (best 0.88) |
| 7TJX | Yeast ATP synthase F1 region state 1BINDING(A-D) with 10 mm ATP | electron microscopy | A, B, C | ATP, MG, ADP, PO4 | — |
| 7TJY | Yeast ATP synthase State 1catalytic(a) without exogenous ATP backbone model | electron microscopy | A, B, C | — | 14 (best 0.82) |
| 7TJZ | Yeast ATP synthase State 1catalytic(b) without exogenous ATP backbone model | electron microscopy | A, B, C | — | 14 (best 0.82) |
| 7TJZ | Yeast ATP synthase state 1CATALYTIC(B) without exogenous ATP backbone model | electron microscopy | A, B, C | — | — |
| 7TK0 | Yeast ATP synthase State 1catalytic(c) without exogenous ATP backbone model | electron microscopy | A, B, C | — | 14 (best 0.76) |
| 7TK1 | Yeast ATP synthase State 1catalytic(d) without exogenous ATP backbone model | electron microscopy | A, B, C | — | 10 (best 0.81) |
| 7TK1 | Yeast ATP synthase state 1CATALYTIC(D) without exogenous ATP backbone model | electron microscopy | A, B, C | — | — |
| 7TK2 | Yeast ATP synthase State 1binding(a) with 10 mM ATP backbone model | electron microscopy | A, B, C | — | 11 (best 0.82) |
| 7TK2 | Yeast ATP synthase state 1BINDING(A) with 10 mm ATP backbone model | electron microscopy | A, B, C | — | — |
| 7TK3 | Yeast ATP synthase State 1binding(b) with 10 mM ATP backbone model | electron microscopy | A, B, C | — | 13 (best 0.80) |
| 7TK4 | Yeast ATP synthase State 1binding(c) with 10 mM ATP backbone model | electron microscopy | A, B, C | — | — |
| 7TK4 | Yeast ATP synthase state 1BINDING(C) with 10 mm ATP backbone model | electron microscopy | A, B, C | — | — |
| 7TK5 | Yeast ATP synthase State 1binding(d) with 10 mM ATP backbone model | electron microscopy | A, B, C | — | 12 (best 0.82) |
| 7TK5 | Yeast ATP synthase state 1BINDING(D) with 10 mm ATP backbone model | electron microscopy | A, B, C | — | — |
| 7TK6 | Yeast ATP synthase State 1catalytic(a) with 10 mM ATP backbone model | electron microscopy | A, B, C | — | 13 (best 0.82) |
| 7TK7 | Yeast ATP synthase State 1catalytic(b) with 10 mM ATP backbone model | electron microscopy | A, B, C | — | 14 (best 0.77) |
| 7TK7 | Yeast ATP synthase state 1CATALYTIC(B) with 10 mm ATP backbone model | electron microscopy | A, B, C | — | — |
| 7TK8 | Yeast ATP synthase State 1catalytic(c) with 10 mM ATP backbone model | electron microscopy | A, B, C | — | 10 (best 0.77) |
| 7TK8 | Yeast ATP synthase state 1CATALYTIC(C) with 10 mm ATP backbone model | electron microscopy | A, B, C | — | — |
| 7TK9 | Yeast ATP synthase State 1catalytic(d) with 10 mM ATP backbone model | electron microscopy | A, B, C | — | 13 (best 0.77) |
| 7TK9 | Yeast ATP synthase state 1CATALYTIC(D) with 10 mm ATP backbone model | electron microscopy | A, B, C | — | — |
| 7TKA | Yeast ATP synthase State 1catalytic(e) with 10 mM ATP backbone model | electron microscopy | A, B, C | — | 12 (best 0.83) |
| 7TKA | Yeast ATP synthase state 1CATALYTIC(E) with 10 mm ATP backbone model | electron microscopy | A, B, C | — | — |
| 7TKB | Yeast ATP synthase State 1catalytic(f) with 10 mM ATP backbone model | electron microscopy | A, B, C | — | — |
| 7TKB | Yeast ATP synthase state 1CATALYTIC(F) with 10 mm ATP backbone model | electron microscopy | A, B, C | — | — |
35 records more on the page itself.
Ligands
Experiment against prediction
- 3OEH chain C against the predicted model P07251: TM-score 1.00, RMSD 0.56 Å
- 3OEH chain C against the predicted model P07251: TM-score 1.00, RMSD 0.56 Å
- 2HLD chain U against the predicted model P07251: TM-score 0.99, RMSD 0.56 Å
- 2HLD chain U against the predicted model P07251: TM-score 0.99, RMSD 0.56 Å
- 6CP3 chain C against the predicted model P07251: TM-score 0.99, RMSD 0.57 Å
- 6CP3 chain C against the predicted model P07251: TM-score 0.99, RMSD 0.57 Å
- 3OEE chain L against the predicted model P07251: TM-score 0.99, RMSD 0.56 Å
- 3OEE chain L against the predicted model P07251: TM-score 0.99, RMSD 0.56 Å
- 3OE7 chain C against the predicted model P07251: TM-score 0.99, RMSD 0.58 Å
- 3OE7 chain C against the predicted model P07251: TM-score 0.99, RMSD 0.58 Å
Elsewhere
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