UniProt P07097
Acetyl-CoA acetyltransferase (P07097)
Acetyl-CoA acetyltransferase (UniProt P07097), EC 2.3.1.9: 58 experimental structures on GenesisL1, 5 ligands bound, 51 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P07097
- Protein
- Acetyl-CoA acetyltransferase
- EC
- 2.3.1.9
- Experimental structures
- 58
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 51 · 3 records with a druggable one
Structures
58 records of P07097 in the MolNFT archive: 58 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DLU | Unliganded biosynthetic thiolase from zoogloea ramigera | x-ray diffraction | A, B, C, D | — | — |
| 1DLU | Unliganded biosynthetic thiolase from zoogloea ramigera | x-ray diffraction | A, B, C, D | — | — |
| 1DLV | Biosynthetic thiolase from zoogloea ramigera in complex with CoA | x-ray diffraction | A, B, C, D | — | — |
| 1DLV | Biosynthetic thiolase from zoogloea ramigera in complex with CoA | x-ray diffraction | A, B, C, D | — | — |
| 1DM3 | Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-CoA | x-ray diffraction | A, B, C, D | — | — |
| 1DM3 | Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-CoA | x-ray diffraction | A, B, C, D | — | — |
| 1M1O | Crystal structure of biosynthetic thiolase, C89A mutant, complexed with acetoacetyl-CoA | x-ray diffraction | A, B, C, D | — | — |
| 1M1O | Crystal structure of biosynthetic thiolase, C89A mutant, complexed with acetoacetyl-CoA | x-ray diffraction | A, B, C, D | — | — |
| 1M1T | Biosynthetic thiolase, Q64A mutant | x-ray diffraction | A, B, C, D | — | — |
| 1M1T | Biosynthetic thiolase, Q64A mutant | x-ray diffraction | A, B, C, D | — | — |
| 1M3K | biosynthetic thiolase, inactive C89A mutant | x-ray diffraction | A, B, C, D | — | — |
| 1M3K | Biosynthetic thiolase, inactive C89A mutant | x-ray diffraction | A, B, C, D | — | — |
| 1M3Z | Biosynthetic thiolase, C89A mutant, complexed with acetyl coenzyme A | x-ray diffraction | A, B, C, D | — | — |
| 1M3Z | Biosynthetic thiolase, C89A mutant, complexed with acetyl coenzyme a | x-ray diffraction | A, B, C, D | — | — |
| 1M4S | Biosynthetic thiolase, Cys89 acetylated, unliganded form | x-ray diffraction | A, B, C, D | — | — |
| 1M4S | Biosynthetic thiolase, CYS89 acetylated, unliganded form | x-ray diffraction | A, B, C, D | — | — |
| 1M4T | Biosynthetic thiolase, Cys89 butyrylated | x-ray diffraction | A, B, C, D | — | — |
| 1M4T | Biosynthetic thiolase, CYS89 butyrylated | x-ray diffraction | A, B, C, D | — | — |
| 1NL7 | Z. ramigera biosynthetic thiolase, acetylated enzyme complexed with CoA at pH 9.5 | x-ray diffraction | A, B, C, D | — | — |
| 1NL7 | Z. ramigera biosynthetic thiolase, acetylated enzyme complexed with CoA at pH 9.5 | x-ray diffraction | A, B, C, D | — | — |
| 1OU6 | Biosynthetic thiolase from Zoogloea ramigera in complex with acetyl-O-pantetheine-11-pivalate | x-ray diffraction | A, B, C, D | — | — |
| 1OU6 | Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-O- pantetheine-11-pivalate | x-ray diffraction | A, B, C, D | — | — |
| 1QFL | Biosynthetic thiolase from zoogloea ramigera in complex with a reaction intermediate. | x-ray diffraction | A, B, C, D | — | — |
| 1QFL | Biosynthetic thiolase from zoogloea ramigera in complex with a reaction intermediate. | x-ray diffraction | A, B, C, D | — | — |
| 2VTZ | Biosynthetic thiolase from Z. ramigera. Complex of the C89A mutant with coenzyme A. | x-ray diffraction | A, B, C, D | — | — |
| 2VTZ | Biosynthetic thiolase from Z. ramigera. complex of the C89A mutant with coenzyme a. | x-ray diffraction | A, B, C, D | — | — |
| 2VU0 | Biosynthetic thiolase from Z. ramigera. Complex of the oxidised enzyme with coenzyme A. | x-ray diffraction | A, B, C, D | — | — |
| 2VU0 | Biosynthetic thiolase from Z. ramigera. complex of the oxidised enzyme with coenzyme a. | x-ray diffraction | A, B, C, D | — | — |
| 2VU1 | Biosynthetic thiolase from Z. ramigera. Complex of with O-pantheteine- 11-pivalate. | x-ray diffraction | A, B, C, D | — | — |
| 2VU1 | Biosynthetic thiolase from Z. ramigera. complex of with O-pantheteine- 11-pivalate. | x-ray diffraction | A, B, C, D | — | — |
| 2VU2 | Biosynthetic thiolase from Z. ramigera. Complex with S-pantetheine-11- pivalate. | x-ray diffraction | A, B, C, D | — | — |
| 2VU2 | Biosynthetic thiolase from Z. ramigera. complex with S-pantetheine-11- pivalate. | x-ray diffraction | A, B, C, D | — | — |
| 2WKT | Biosynthetic thiolase from Z. ramigera. complex of the N316A mutant with coenzyme a. | x-ray diffraction | A, B, C, D | — | — |
| 2WKT | Biosynthetic thiolase from Z. ramigera. complex of the N316A mutant with coenzyme a. | x-ray diffraction | A, B, C, D | — | — |
| 2WKU | Biosynthetic thiolase from Z. ramigera. the N316H mutant. | x-ray diffraction | A, B, C, D | — | — |
| 2WKU | Biosynthetic thiolase from Z. ramigera. the N316H mutant. | x-ray diffraction | A, B, C, D | — | — |
| 2WKV | Biosynthetic thiolase from Z. ramigera. complex of the N316D mutant with coenzyme a. | x-ray diffraction | A, B, C, D | — | — |
| 2WKV | Biosynthetic thiolase from Z. ramigera. complex of the N316D mutant with coenzyme a. | x-ray diffraction | A, B, C, D | — | — |
| 2WL4 | Biosynthetic thiolase from Z. ramigera. complex of the H348A mutant with coenzyme a. | x-ray diffraction | A, B, C, D | — | — |
| 2WL4 | Biosynthetic thiolase from Z. ramigera. complex of the H348A mutant with coenzyme a. | x-ray diffraction | A, B, C, D | — | — |
| 2WL5 | Biosynthetic thiolase from Z. ramigera. complex of the H348N mutant with coenzyme a. | x-ray diffraction | A, B, C, D | — | — |
| 2WL5 | Biosynthetic thiolase from Z. ramigera. complex of the H348N mutant with coenzyme a. | x-ray diffraction | A, B, C, D | — | — |
| 2WL6 | Biosynthetic thiolase from Z. ramigera. the N316H-H348N mutant. | x-ray diffraction | A, B, C, D | — | — |
| 2WL6 | Biosynthetic thiolase from Z. ramigera. the N316H-H348N mutant. | x-ray diffraction | A, B, C, D | — | — |
| 7LBZ | Zoogloea ramigera biosynthetic thiolase Y218E mutant | x-ray diffraction | A, B, C, D | COA, SO4 | 17 (best 0.70) |
| 7LBZ | Zoogloea ramigera biosynthetic thiolase Y218E mutant | x-ray diffraction | A, B, C, D | COA, SO4 | — |
| 7LCA | Zoogloea ramigera biosynthetic thiolase Y218E/DELH221 mutant | x-ray diffraction | A, B, C, D | SO4, COA, CL | — |
| 7LCL | Zoogloea ramigera biosynthetic thiolase Q183Y mutant | x-ray diffraction | A, B, C, D | SO4, COA, NH4 | — |
| 7LD2 | Zoogloea ramigera biosynthetic thiolase Q183Y mutant, RbCl soak | x-ray diffraction | A, B, C, D | SO4, COA, RB, CL | 16 (best 0.79) |
| 7LD2 | Zoogloea ramigera biosynthetic thiolase Q183Y mutant, rbcl soak | x-ray diffraction | A, B, C, D | SO4, COA, RB, CL | — |
| 7LDC | Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E mutant | x-ray diffraction | A, B, C, D | SO4, COA | — |
| 7LDT | Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E mutant, RbCl soak | x-ray diffraction | A, B, C, D | SO4, COA, RB | 18 (best 0.79) |
| 7LDT | Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E mutant, rbcl soak | x-ray diffraction | A, B, C, D | SO4, COA, RB | — |
| 7LDU | Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E/DELH221 mutant | x-ray diffraction | A, B, C, D | SO4, COA, CL | — |
| 7LDV | Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E/delH221/S227K mutant | x-ray diffraction | A, B, C, D | SO4, COA, NH4, CL | — |
| 7LDV | Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E/DELH221/S227K mutant | x-ray diffraction | A, B, C, D | SO4, COA, NH4, CL | — |
| 7LDW | Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E/DELH221/S227K/G248T mutant | x-ray diffraction | A, B, C, D | SO4, COA, NH4 | — |
| P07097 | AlphaFold monomer V2.0 prediction for acetyl-CoA acetyltransferase (P07097) | — | — | — |
Ligands
Elsewhere
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