UniProt P06850
Corticoliberin (P06850)
Corticoliberin (UniProt P06850): 10 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P06850
- Protein
- Corticoliberin
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
11 records of P06850 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GO9 | Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r… | solution nmr | A | — | — |
| 1GO9 | Monitoring the structural consequences of PHE12-->D-PHE12 and LEU15-->AIB15 substitution in H/R… | solution nmr | A | — | — |
| 1GOE | Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r… | solution nmr | A | — | — |
| 1GOE | Monitoring the structural consequences of PHE12-->D-PHE12 and LEU15-->AIB15 substitution in H/R… | solution nmr | A | — | — |
| 3EHT | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type… | x-ray diffraction | B | — | — |
| 3EHT | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type… | x-ray diffraction | B | — | — |
| 3EHU | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type… | x-ray diffraction | C, D | — | — |
| 3EHU | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type… | x-ray diffraction | C, D | — | — |
| 6P9X | CRF1 Receptor Gs GPCR protein complex with CRF1 peptide | electron microscopy | P | — | 3 (best 0.63) |
| 6P9X | CRF1 receptor gs GPCR protein complex with CRF1 peptide | electron microscopy | P | — | — |
| P06850 | AlphaFold monomer V2.0 prediction for corticoliberin (P06850) | predicted | A | — | — |
Experiment against prediction
- 6P9X chain P against the predicted model P06850: TM-score 0.71, RMSD 1.75 Å
- 6P9X chain P against the predicted model P06850: TM-score 0.71, RMSD 1.75 Å
- 3EHT chain B against the predicted model P06850: TM-score 0.71, RMSD 0.41 Å
- 3EHT chain B against the predicted model P06850: TM-score 0.71, RMSD 0.41 Å
- 3EHU chain C against the predicted model P06850: TM-score 0.66, RMSD 0.41 Å
- 3EHU chain C against the predicted model P06850: TM-score 0.66, RMSD 0.41 Å
- 1GO9 chain A against the predicted model P06850: TM-score 0.58, RMSD 1.76 Å
- 1GO9 chain A against the predicted model P06850: TM-score 0.58, RMSD 1.76 Å
- 1GOE chain A against the predicted model P06850: TM-score 0.57, RMSD 2.28 Å
- 1GOE chain A against the predicted model P06850: TM-score 0.57, RMSD 2.28 Å
Elsewhere
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