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UniProt P06633

Imidazoleglycerol-phosphate dehydratase (P06633)

Imidazoleglycerol-phosphate dehydratase (UniProt P06633), EC 4.2.1.19: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction…

UniProt
P06633
Protein
Imidazoleglycerol-phosphate dehydratase
EC
4.2.1.19
Experimental structures
2
Predicted models
1
Ligands
2
Pockets
20 · 1 record with a druggable one

Structures

3 records of P06633 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6EZMImidazoleglycerol-phosphate dehydratase from Saccharomyces cerevisiaeelectron microscopyU, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, V, W, XMN, 5LD20 (best 0.79)
6EZMImidazoleglycerol-phosphate dehydratase from saccharomyces cerevisiaeelectron microscopyU, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, V, W, XMN, 5LD—
P06633AlphaFold monomer V2.0 prediction for imidazoleglycerol-phosphate dehydratase (P06633)predictedA——

Ligands

  • 5LD · [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid · in 2 records
  • MN · Manganese (II) ion · in 2 records

Experiment against prediction

Elsewhere

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