UniProt P06463
peptide E6 (P06463)
peptide E6 (UniProt P06463): 18 experimental structures on GenesisL1, 3 ligands bound, 9 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P06463
- Protein
- peptide E6
- Experimental structures
- 18
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 9 · 3 records with a druggable one
Structures
18 records of P06463 in the MolNFT archive: 18 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2I04 | X-ray crystal structure of MAGI-1 PDZ1 bound to the C-terminal peptide of HPV18 E6 | x-ray diffraction | C, D | — | — |
| 2I04 | X-ray crystal structure of magi-1 PDZ1 bound to the C- terminal peptide of HPV18 E6 | x-ray diffraction | C, D | — | — |
| 2I0I | X-ray crystal structure of Sap97 PDZ3 bound to the C-terminal peptide of HPV18 E6 | x-ray diffraction | D, E, F | — | 1 (best 0.43) |
| 2I0I | X-ray crystal structure of SAP97 PDZ3 bound to the C- terminal peptide of HPV18 E6 | x-ray diffraction | D, E, F | — | — |
| 2I0L | X-ray crystal structure of Sap97 PDZ2 bound to the C-terminal peptide of HPV18 E6. | x-ray diffraction | C, D | — | — |
| 2I0L | X-ray crystal structure of SAP97 PDZ2 bound to the C- terminal peptide of HPV18 E6. | x-ray diffraction | C, D | — | — |
| 4JOR | CFTR Associated Ligand (CAL) PDZ domain bound to HPV18 E6 oncoprotein C-terminal peptide… | x-ray diffraction | C, D | — | — |
| 4JOR | Cftr associated ligand (cal) PDZ domain bound to HPV18 E6 oncoprotein C-terminal peptide… | x-ray diffraction | C, D | — | — |
| 5K4F | CAL PDZ mutant C319A with a peptide | x-ray diffraction | C, D | — | 1 (best 0.26) |
| 5K4F | Cal PDZ mutant C319A with a peptide | x-ray diffraction | C, D | — | — |
| 6SJV | Structure of HPV18 E6 oncoprotein in complex with mutant E6AP LxxLL motif | x-ray diffraction | A | GLC, ZN | — |
| 6SJV | Structure of HPV18 E6 oncoprotein in complex with mutant E6AP lxxll motif | x-ray diffraction | A | GLC, ZN | — |
| 6ZFD | 14-3-3 zeta bound to the phosphorylated 18E6 C-terminus | x-ray diffraction | A, B | — | 3 (best 0.53) |
| 6ZFD | 14-3-3 zeta bound to the phosphorylated 18E6 C-terminus | x-ray diffraction | A, B | — | — |
| 6ZFG | 14-3-3 zeta chimera with 18E6 and fusicoccin | x-ray diffraction | A, B | FSC | 3 (best 0.58) |
| 6ZFG | 14-3-3 zeta chimera with 18E6 and fusicoccin | x-ray diffraction | A, B | FSC | — |
| 8B82 | Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide | x-ray diffraction | C, D | — | 1 (best 0.72) |
| 8OEP | Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide | x-ray diffraction | B, D | — | — |
Ligands
Experiment against prediction
- 6ZFD chain B against the predicted model P63104: TM-score 0.94, RMSD 1.29 Å
- 6ZFD chain B against the predicted model P63104: TM-score 0.94, RMSD 1.29 Å
- 6ZFG chain A against the predicted model P63104: TM-score 0.94, RMSD 1.34 Å
- 6ZFG chain A against the predicted model P63104: TM-score 0.94, RMSD 1.34 Å
- 6ZFG chain B against the predicted model P63104: TM-score 0.94, RMSD 1.10 Å
- 6ZFG chain B against the predicted model P63104: TM-score 0.94, RMSD 1.10 Å
- 6ZFD chain A against the predicted model P63104: TM-score 0.94, RMSD 1.33 Å
- 6ZFD chain A against the predicted model P63104: TM-score 0.94, RMSD 1.33 Å
- 6SJV chain A against the predicted model Q05086: TM-score 0.32, RMSD 7.12 Å
- 6SJV chain A against the predicted model Q05086: TM-score 0.32, RMSD 7.12 Å
Elsewhere
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