UniProt P06149
D-lactate dehydrogenase (P06149)
D-lactate dehydrogenase (UniProt P06149), EC 1.1.1.28: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P06149
- Protein
- D-lactate dehydrogenase
- EC
- 1.1.1.28
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
3 records of P06149 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1F0X | Crystal structure of D-lactate dehydrogenase, a peripheral membrane respiratory enzyme. | x-ray diffraction | A, B | FAD | 8 (best 0.83) |
| 1F0X | Crystal structure of D-lactate dehydrogenase, a peripheral membrane respiratory enzyme. | x-ray diffraction | A, B | — | — |
| P06149 | AlphaFold monomer V2.0 prediction for quinone-dependent D-lactate dehydrogenase (P06149) | predicted | A | — | — |
Ligands
- FAD · Flavin-adenine dinucleotide · in 1 record
Experiment against prediction
- 1F0X chain A against the predicted model P06149: TM-score 0.98, RMSD 1.07 Å
- 1F0X chain A against the predicted model P06149: TM-score 0.98, RMSD 1.07 Å
- 1F0X chain B against the predicted model P06149: TM-score 0.98, RMSD 1.19 Å
- 1F0X chain B against the predicted model P06149: TM-score 0.98, RMSD 1.19 Å
Elsewhere
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