UniProt P05543
Thyroxine-binding globulin (P05543)
Thyroxine-binding globulin (UniProt P05543): 18 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P05543
- Protein
- Thyroxine-binding globulin
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 6 · 0 records with a druggable one
Structures
19 records of P05543 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2CEO | thyroxine-binding globulin complex with thyroxine | x-ray diffraction | A, B | — | — |
| 2CEO | Thyroxine-binding globulin complex with thyroxine | x-ray diffraction | A, B | — | — |
| 2RIV | Crystal structure of the reactive loop cleaved human Thyroxine Binding Globulin | x-ray diffraction | A, B | — | — |
| 2RIV | Crystal structure of the reactive loop cleaved human thyroxine binding globulin | x-ray diffraction | A, B | — | — |
| 2RIW | The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine | x-ray diffraction | A, B | — | — |
| 2RIW | The reactive loop cleaved human thyroxine binding globulin complexed with thyroxine | x-ray diffraction | A, B | — | — |
| 2XN3 | Crystal structure of thyroxine-binding globulin complexed with mefenamic acid | x-ray diffraction | A, B | — | — |
| 2XN3 | Crystal structure of thyroxine-binding globulin complexed with mefenamic acid | x-ray diffraction | A, B | — | — |
| 2XN5 | Crystal structure of thyroxine-binding globulin complexed with Furosemide | x-ray diffraction | A, B | — | — |
| 2XN5 | Crystal structure of thyroxine-binding globulin complexed with furosemide | x-ray diffraction | A, B | — | — |
| 2XN6 | Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein | x-ray diffraction | A, B | — | — |
| 2XN6 | Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein | x-ray diffraction | A, B | — | — |
| 2XN7 | Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein (T405-CF) | x-ray diffraction | A, B | — | — |
| 2XN7 | Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein (T405-cf) | x-ray diffraction | A, B | — | — |
| 4X30 | Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom… | x-ray diffraction | A | — | — |
| 4X30 | Crystal structure of human thyroxine-binding globulin complexed with thyroine at 1.55 ångström… | x-ray diffraction | A | — | — |
| 4YIA | Structural mechanism of hormone release in thyroxine binding globulin | x-ray diffraction | A, B | — | — |
| 4YIA | Structural mechanism of hormone release in thyroxine binding globulin | x-ray diffraction | A, B | — | — |
| P05543 | AlphaFold monomer V2.0 prediction for thyroxine-binding globulin (P05543) | predicted | A | — | 6 (best 0.48) |
Experiment against prediction
- 4X30 chain A against the predicted model P05543: TM-score 0.97, RMSD 1.18 Å
- 4X30 chain A against the predicted model P05543: TM-score 0.97, RMSD 1.18 Å
- 2CEO chain A against the predicted model P05543: TM-score 0.96, RMSD 1.63 Å
- 2CEO chain A against the predicted model P05543: TM-score 0.96, RMSD 1.63 Å
- 4YIA chain A against the predicted model P05543: TM-score 0.92, RMSD 1.77 Å
- 4YIA chain A against the predicted model P05543: TM-score 0.92, RMSD 1.77 Å
- 2RIW chain A against the predicted model P05543: TM-score 0.92, RMSD 1.79 Å
- 2XN3 chain A against the predicted model P05543: TM-score 0.92, RMSD 1.80 Å
- 2XN3 chain A against the predicted model P05543: TM-score 0.92, RMSD 1.80 Å
- 2XN6 chain A against the predicted model P05543: TM-score 0.92, RMSD 1.80 Å
Elsewhere
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