UniProt P05364
Beta-lactamase (P05364)
Beta-lactamase (UniProt P05364), EC 3.5.2.6: 22 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P05364
- Protein
- Beta-lactamase
- EC
- 3.5.2.6
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 3 · 1 record with a druggable one
Structures
23 records of P05364 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BLS | Crystallographic structure of a phosphonate derivative of the enterobacter cloacae P99… | x-ray diffraction | A, B | — | — |
| 1BLS | Crystallographic structure of a phosphonate derivative of the enterobacter cloacae P99… | x-ray diffraction | A, B | — | — |
| 1GCE | Structure of the beta-lactamase of enterobacter cloacae GC1 | x-ray diffraction | A | — | — |
| 1GCE | Structure of the beta-lactamase of enterobacter cloacae GC1 | x-ray diffraction | A | — | — |
| 1RGZ | Enterobacter cloacae GC1 Class C beta-Lactamase Complexed with Transition-State Analog of Cefotaxime | x-ray diffraction | A | — | — |
| 1RGZ | Enterobacter cloacae GC1 class C beta-lactamase complexed with transition-state analog of cefotaxime | x-ray diffraction | A | — | — |
| 1XX2 | Refinement of P99 beta-lactamase from Enterobacter cloacae | x-ray diffraction | A, B | — | — |
| 1XX2 | Refinement of P99 beta-lactamase from enterobacter cloacae | x-ray diffraction | A, B | — | — |
| 1Y54 | Crystal structure of the native class C beta-lactamase from Enterobacter cloacae 908R complexed… | x-ray diffraction | A | — | — |
| 1Y54 | Crystal structure of the native class C beta-lactamase from enterobacter cloacae 908R complexed… | x-ray diffraction | A | — | — |
| 2Q9M | 4-Substituted Trinems as Broad Spectrum-Lactamase Inhibitors: Structure-based Design, Synthesis and… | x-ray diffraction | A | — | — |
| 2Q9M | 4-substituted trinems as broad spectrum-lactamase inhibitors: structure-based design, synthesis and… | x-ray diffraction | A | — | — |
| 2Q9N | 4-Substituted Trinems as Broad Spectrum-Lactamase Inhibitors: Structure-based Design, Synthesis and… | x-ray diffraction | A | — | — |
| 2Q9N | 4-substituted trinems as broad spectrum-lactamase inhibitors: structure-based design, synthesis and… | x-ray diffraction | A | — | — |
| 3S4X | Crystal structure of the Asn152Gly mutant of P99 beta-lactamase | x-ray diffraction | A | — | — |
| 3S4X | Crystal structure of the ASN152GLY mutant of P99 beta-lactamase | x-ray diffraction | A | — | — |
| 4XUX | Structure of ampC bound to RPX-7009 at 1.75 A | x-ray diffraction | A | — | — |
| 4XUX | Structure of ampc bound to rpx-7009 at 1.75 a | x-ray diffraction | A | — | — |
| 5HAI | P99 beta-lactamase mutant - S64G | x-ray diffraction | A | PO4 | — |
| 5HAI | P99 beta-lactamase mutant - S64G | x-ray diffraction | A | — | — |
| 5XHR | Crystal structure of P99 beta-lactamase in complex with a penicillin derivative MPC-1 | x-ray diffraction | A | PXH | 3 (best 0.61) |
| 5XHR | Crystal structure of P99 beta-lactamase in complex with a penicillin derivative mpc-1 | x-ray diffraction | A | PXH | — |
| P05364 | AlphaFold monomer V2.0 prediction for beta-lactamase (P05364) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1XX2 chain A against the predicted model P05364: TM-score 1.00, RMSD 0.41 Å
- 1XX2 chain A against the predicted model P05364: TM-score 1.00, RMSD 0.41 Å
- 1XX2 chain B against the predicted model P05364: TM-score 1.00, RMSD 0.43 Å
- 1XX2 chain B against the predicted model P05364: TM-score 1.00, RMSD 0.43 Å
- 4XUX chain A against the predicted model P05364: TM-score 1.00, RMSD 0.45 Å
- 4XUX chain A against the predicted model P05364: TM-score 1.00, RMSD 0.45 Å
- 5XHR chain A against the predicted model P05364: TM-score 1.00, RMSD 0.46 Å
- 5XHR chain A against the predicted model P05364: TM-score 1.00, RMSD 0.46 Å
- 2Q9N chain A against the predicted model P05364: TM-score 1.00, RMSD 0.47 Å
- 2Q9N chain A against the predicted model P05364: TM-score 1.00, RMSD 0.47 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.