UniProt P05362
Intercellular adhesion molecule 1 (P05362)
Intercellular adhesion molecule 1 (UniProt P05362): 24 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P05362
- Protein
- Intercellular adhesion molecule 1
- Experimental structures
- 24
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 3 · 1 record with a druggable one
Structures
25 records of P05362 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1D3E | Cryo-EM structure of human rhinovirus 16 (HRV16) complexed with a two-domain fragment of its… | electron microscopy | 1 | — | — |
| 1D3E | Cryo-EM structure of human rhinovirus 16 (HRV16) complexed with a two- domain fragment of its… | electron microscopy | 1 | — | — |
| 1D3I | Cryo-EM structure of human rhinovirus 14 (HRV14) complexed with a two-domain fragment of its… | electron microscopy | I | — | — |
| 1D3I | Cryo-EM structure of human rhinovirus 14 (HRV14) complexed with a two- domain fragment of its… | electron microscopy | I | — | — |
| 1D3L | D1D2-icam-1 fully glycosylated, variation of D1-D2 interdomain angle in different crystal… | x-ray diffraction | A | — | — |
| 1D3L | D1D2-icam-1 fully glycosylated, variation of D1-D2 interdomain angle in different crystal… | x-ray diffraction | A | — | — |
| 1IAM | Structure of the two amino-terminal domains of human intercellular adhesion molecule-1, icam-1 | x-ray diffraction | A | — | — |
| 1IAM | Structure of the two amino-terminal domains of human intercellular adhesion molecule-1, icam-1 | x-ray diffraction | A | — | — |
| 1IC1 | The crystal structure for the N-terminal two domains of icam-1 | x-ray diffraction | A, B | — | — |
| 1IC1 | The crystal structure for the N-terminal two domains of icam-1 | x-ray diffraction | A, B | — | — |
| 1MQ8 | Crystal structure of alphaL I domain in complex with ICAM-1 | x-ray diffraction | A, C | — | — |
| 1MQ8 | Crystal structure of alphal I domain in complex with icam-1 | x-ray diffraction | A, C | — | — |
| 1P53 | The Crystal Structure of ICAM-1 D3-D5 fragment | x-ray diffraction | A, B | — | — |
| 1P53 | The crystal structure of icam-1 D3-D5 fragment | x-ray diffraction | A, B | — | — |
| 1Z7Z | Cryo-em structure of human coxsackievirus A21 complexed with five domain icam-1kilifi | electron microscopy | I | — | — |
| 1Z7Z | Cryo-EM structure of human coxsackievirus A21 complexed with five domain icam-1KILIFI | electron microscopy | I | — | — |
| 3TCX | Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native… | x-ray diffraction | A, C, E, G, I, K, M, O, Q, S, U, W, Y, a | — | — |
| 3TCX | Structure of engineered single domain icam-1 D1 with high-affinity al integrin I domain of native… | x-ray diffraction | A, C, E, G, I, K, M, O, Q, S, U, W, Y, a | — | — |
| 5MZA | The DBLb domain of PF11_0521 PfEMP1 bound to human ICAM-1 | x-ray diffraction | B | NAG, IHP | — |
| 5MZA | The dblb domain of PF11_0521 PFEMP1 bound to human icam-1 | x-ray diffraction | B | NAG, IHP | — |
| 6EIT | Coxsackievirus A24V in complex with the D1-D2 fragment of icam-1 | electron microscopy | 4 | — | — |
| 6S8U | Structure of the PfEMP1 IT4var13 DBLbeta domain bound to ICAM-1 | x-ray diffraction | B | NAG | 3 (best 0.71) |
| 6S8U | Structure of the PFEMP1 IT4VAR13 dblbeta domain bound to icam-1 | x-ray diffraction | B | NAG | — |
| 7BG7 | HRV14 in complex with its receptor icam-1 | electron microscopy | B | — | — |
| P05362 | AlphaFold monomer V2.0 prediction for intercellular adhesion molecule 1 (P05362) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1D3I chain I against the predicted model P05362: TM-score 0.98, RMSD 0.68 Å
- 1D3I chain I against the predicted model P05362: TM-score 0.98, RMSD 0.68 Å
- 1MQ8 chain A against the predicted model P05362: TM-score 0.97, RMSD 0.90 Å
- 1MQ8 chain A against the predicted model P05362: TM-score 0.97, RMSD 0.90 Å
- 1IAM chain A against the predicted model P05362: TM-score 0.97, RMSD 0.88 Å
- 1IAM chain A against the predicted model P05362: TM-score 0.97, RMSD 0.88 Å
- 6S8U chain B against the predicted model P05362: TM-score 0.97, RMSD 0.88 Å
- 6S8U chain B against the predicted model P05362: TM-score 0.97, RMSD 0.88 Å
- 1D3L chain A against the predicted model P05362: TM-score 0.97, RMSD 0.97 Å
- 1D3L chain A against the predicted model P05362: TM-score 0.97, RMSD 0.97 Å
Elsewhere
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