UniProt P05156
Complement factor I (P05156)
Complement factor I (UniProt P05156), EC 3.4.21.45: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P05156
- Protein
- Complement factor I
- EC
- 3.4.21.45
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 10 · 1 record with a druggable one
Structures
5 records of P05156 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XRC | Human complement factor I | x-ray diffraction | A, B, C, D | — | — |
| 2XRC | Human complement factor I | x-ray diffraction | A, B, C, D | — | — |
| 5O32 | The structure of complement complex | x-ray diffraction | D, I, H, J | CA, NAG | 10 (best 0.86) |
| 5O32 | The structure of complement complex | x-ray diffraction | D, I, H, J | CA, NAG | — |
| P05156 | AlphaFold monomer V2.0 prediction for complement factor I (P05156) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5O32 chain D against the predicted model P05156: TM-score 0.97, RMSD 1.32 Å
- 5O32 chain D against the predicted model P05156: TM-score 0.97, RMSD 1.32 Å
- 5O32 chain H against the predicted model P05156: TM-score 0.97, RMSD 1.26 Å
- 5O32 chain H against the predicted model P05156: TM-score 0.97, RMSD 1.26 Å
- 5O32 chain J against the predicted model P05156: TM-score 0.96, RMSD 1.40 Å
- 5O32 chain J against the predicted model P05156: TM-score 0.96, RMSD 1.40 Å
- 5O32 chain I against the predicted model P05156: TM-score 0.95, RMSD 1.43 Å
- 5O32 chain I against the predicted model P05156: TM-score 0.95, RMSD 1.43 Å
- 2XRC chain C against the predicted model P05156: TM-score 0.95, RMSD 1.78 Å
- 2XRC chain C against the predicted model P05156: TM-score 0.95, RMSD 1.78 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.