UniProt P05132
cAMP-dependent protein kinase catalytic subunit alpha (P05132)
cAMP-dependent protein kinase catalytic subunit alpha (UniProt P05132), EC 2.7.11.11: 159 experimental structures on GenesisL1, 6 ligands bound, 59 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P05132
- Protein
- cAMP-dependent protein kinase catalytic subunit alpha
- EC
- 2.7.11.11
- Experimental structures
- 159
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 59 · 9 records with a druggable one
Structures
159 records of P05132 in the MolNFT archive: 159 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1APM | 2.0 ångström refined crystal structure of the catalytic subunit of camp-dependent protein kinase… | x-ray diffraction | E | — | — |
| 1APM | 2.0 ångström refined crystal structure of the catalytic subunit of camp-dependent protein kinase… | x-ray diffraction | E | — | — |
| 1ATP | 2.2 angstrom refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase… | x-ray diffraction | E | — | — |
| 1ATP | 2.2 ångström refined crystal structure of the catalytic subunit of camp-dependent protein kinase… | x-ray diffraction | E | — | — |
| 1BKX | A binary complex of the catalytic subunit of camp-dependent protein kinase and adenosine further… | x-ray diffraction | A | — | — |
| 1BKX | A binary complex of the catalytic subunit of camp-dependent protein kinase and adenosine further… | x-ray diffraction | A | — | — |
| 1BX6 | Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic… | x-ray diffraction | A | — | — |
| 1BX6 | Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic… | x-ray diffraction | A | — | — |
| 1FMO | Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of camp-dependent protein… | x-ray diffraction | E | — | — |
| 1FMO | Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of camp-dependent protein… | x-ray diffraction | E | — | — |
| 1J3H | Crystal structure of apoenzyme cAMP-dependent protein kinase catalytic subunit | x-ray diffraction | A, B | — | — |
| 1J3H | Crystal structure of apoenzyme camp-dependent protein kinase catalytic subunit | x-ray diffraction | A, B | — | — |
| 1JBP | Crystal Structure of the Catalytic Subunit of cAMP-dependent Protein Kinase Complexed with a… | x-ray diffraction | E | — | — |
| 1JBP | Crystal structure of the catalytic subunit of camp-dependent protein kinase complexed with a… | x-ray diffraction | E | — | — |
| 1JLU | Crystal Structure of the Catalytic Subunit of cAMP-dependent Protein Kinase Complexed with a… | x-ray diffraction | E | — | — |
| 1JLU | Crystal structure of the catalytic subunit of camp-dependent protein kinase complexed with a… | x-ray diffraction | E | — | — |
| 1L3R | Crystal Structure of a Transition State Mimic of the Catalytic Subunit of cAMP-dependent Protein… | x-ray diffraction | E | — | — |
| 1L3R | Crystal structure of a transition state mimic of the catalytic subunit of camp-dependent protein… | x-ray diffraction | E | — | — |
| 1RDQ | Hydrolysis of ATP in the crystal of Y204A mutant of cAMP-dependent protein kinase | x-ray diffraction | E | — | — |
| 1RDQ | Hydrolysis of ATP in the crystal of Y204A mutant of camp-dependent protein kinase | x-ray diffraction | E | — | — |
| 1RE8 | Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 2 | x-ray diffraction | A | — | — |
| 1RE8 | Crystal structure of camp-dependent protein kinase complexed with balanol analog 2 | x-ray diffraction | A | — | — |
| 1REJ | Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 1 | x-ray diffraction | A | — | — |
| 1REJ | Crystal structure of camp-dependent protein kinase complexed with balanol analog 1 | x-ray diffraction | A | — | — |
| 1REK | Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 8 | x-ray diffraction | A | — | — |
| 1REK | Crystal structure of camp-dependent protein kinase complexed with balanol analog 8 | x-ray diffraction | A | — | — |
| 1SYK | Crystal structure of E230Q mutant of cAMP-dependent protein kinase reveals unexpected apoenzyme… | x-ray diffraction | A, B | — | — |
| 1SYK | Crystal structure of E230Q mutant of camp-dependent protein kinase reveals unexpected apoenzyme… | x-ray diffraction | A, B | — | — |
| 2CPK | Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein… | x-ray diffraction | E | — | — |
| 2CPK | Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein… | x-ray diffraction | E | — | — |
| 2ERZ | Crystal Structure of c-AMP Dependent Kinase (PKA) bound to hydroxyfasudil | x-ray diffraction | E | — | — |
| 2ERZ | Crystal structure of C-AMP dependent kinase (PKA) bound to hydroxyfasudil | x-ray diffraction | E | — | — |
| 2QCS | A complex structure between the Catalytic and Regulatory subunit of Protein Kinase A that… | x-ray diffraction | A | — | — |
| 2QCS | A complex structure between the catalytic and regulatory subunit of protein kinase a that… | x-ray diffraction | A | — | — |
| 2QUR | Crystal Structure of F327A/K285P Mutant of cAMP-dependent Protein Kinase | x-ray diffraction | A | — | — |
| 2QUR | Crystal structure of F327A/K285P mutant of camp-dependent protein kinase | x-ray diffraction | A | — | — |
| 2QVS | Crystal Structure of Type IIa Holoenzyme of cAMP-dependent Protein Kinase | x-ray diffraction | E | — | — |
| 2QVS | Crystal structure of type iia holoenzyme of camp-dependent protein kinase | x-ray diffraction | E | — | — |
| 3FHI | Crystal structure of a complex between the catalytic and regulatory (RI{alpha}) subunits of PKA | x-ray diffraction | A | — | — |
| 3FHI | Crystal structure of a complex between the catalytic and regulatory (RI{ALPHA}) subunits of PKA | x-ray diffraction | A | — | — |
| 3FJQ | Crystal structure of cAMP-dependent protein kinase catalytic subunit alpha in complex with peptide… | x-ray diffraction | E | — | — |
| 3FJQ | Crystal structure of camp-dependent protein kinase catalytic subunit alpha in complex with peptide… | x-ray diffraction | E | — | — |
| 3IDB | Crystal structure of (108-268)RIIb:C holoenzyme of cAMP-dependent protein kinase | x-ray diffraction | A | — | — |
| 3IDB | Crystal structure of (108-268)RIIB:C holoenzyme of camp-dependent protein kinase | x-ray diffraction | A | — | — |
| 3IDC | Crystal structure of (102-265)RIIb:C holoenzyme of cAMP-dependent protein kinase | x-ray diffraction | A | — | — |
| 3IDC | Crystal structure of (102-265)RIIB:C holoenzyme of camp-dependent protein kinase | x-ray diffraction | A | — | — |
| 3J4Q | Pseudo-atomic model of the AKAP18-PKA complex in a bent conformation derived from electron… | electron microscopy | D, E | — | — |
| 3J4Q | Pseudo-atomic model of the AKAP18-PKA complex in a bent conformation derived from electron… | electron microscopy | D, E | — | — |
| 3J4R | Pseudo-atomic model of the AKAP18-PKA Complex in a linear conformation derived from electron… | electron microscopy | D, E | — | — |
| 3J4R | Pseudo-atomic model of the AKAP18-PKA complex in a linear conformation derived from electron… | electron microscopy | D, E | — | — |
| 3O7L | Crystal Structure of phospholamban (1-19):PKA C-subunit:AMP-PNP:Mg2+ complex | x-ray diffraction | B, D | — | — |
| 3O7L | Crystal structure of phospholamban (1-19):PKA C-SUBUNIT:AMP-PNP:MG2+ complex | x-ray diffraction | B, D | — | — |
| 3OW3 | Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors | x-ray diffraction | A | — | — |
| 3OW3 | Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan AKT inhibitors | x-ray diffraction | A | — | — |
| 3PVB | Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase | x-ray diffraction | A | — | — |
| 3PVB | Crystal structure of (73-244)RIA:C holoenzyme of camp-dependent protein kinase | x-ray diffraction | A | — | — |
| 3QAL | Crystal Structure of Arg280Ala mutant of Catalytic subunit of cAMP-dependent Protein Kinase | x-ray diffraction | E | — | — |
| 3QAL | Crystal structure of ARG280ALA mutant of catalytic subunit of camp- dependent protein kinase | x-ray diffraction | E | — | — |
| 3QAM | Crystal Structure of Glu208Ala mutant of catalytic subunit of cAMP-dependent protein kinase | x-ray diffraction | E | — | — |
| 3QAM | Crystal structure of GLU208ALA mutant of catalytic subunit of camp- dependent protein kinase | x-ray diffraction | E | — | — |
99 records more on the page itself.
Ligands
Elsewhere
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