UniProt P05113
Interleukin-5 (P05113)
Interleukin-5 (UniProt P05113): 7 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P05113
- Protein
- Interleukin-5
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
8 records of P05113 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HUL | A novel dimer configuration revealed by the crystal structure at 2.4 ångströms resolution of human… | x-ray diffraction | A, B | — | — |
| 1HUL | A novel dimer configuration revealed by the crystal structure at 2.4 ångströms resolution of human… | x-ray diffraction | A, B | — | — |
| 3QT2 | Structure of a cytokine ligand-receptor complex | x-ray diffraction | C, D, E, F | — | — |
| 3QT2 | Structure of a cytokine ligand-receptor complex | x-ray diffraction | C, D, E, F | — | — |
| 3VA2 | Crystal structure of human Interleukin-5 in complex with its alpha receptor | x-ray diffraction | A, B | — | — |
| 3VA2 | Crystal structure of human interleukin-5 in complex with its alpha receptor | x-ray diffraction | A, B | — | — |
| 8TLD | Structure of the IL-5 Signaling Complex | electron microscopy | C, D | NAG | 4 (best 0.78) |
| P05113 | AlphaFold monomer V2.0 prediction for interleukin-5 (P05113) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
Experiment against prediction
- 3VA2 chain B against the predicted model P05113: TM-score 0.97, RMSD 0.78 Å
- 3VA2 chain B against the predicted model P05113: TM-score 0.97, RMSD 0.78 Å
- 3QT2 chain D against the predicted model P05113: TM-score 0.97, RMSD 0.80 Å
- 3QT2 chain D against the predicted model P05113: TM-score 0.97, RMSD 0.80 Å
- 3VA2 chain A against the predicted model P05113: TM-score 0.97, RMSD 0.76 Å
- 3VA2 chain A against the predicted model P05113: TM-score 0.97, RMSD 0.76 Å
- 3QT2 chain E against the predicted model P05113: TM-score 0.96, RMSD 0.89 Å
- 3QT2 chain E against the predicted model P05113: TM-score 0.96, RMSD 0.89 Å
- 1HUL chain A against the predicted model P05113: TM-score 0.96, RMSD 1.09 Å
- 1HUL chain A against the predicted model P05113: TM-score 0.96, RMSD 1.09 Å
Elsewhere
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