UniProt P05057
Aminoglycoside NucleotidylTransferase (P05057)
Aminoglycoside NucleotidylTransferase (UniProt P05057), EC 2.7.7.-: 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P05057
- Protein
- Aminoglycoside NucleotidylTransferase
- EC
- 2.7.7.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 9 · 3 records with a druggable one
Structures
9 records of P05057 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1KAN | Molecular structure of kanamycin nucleotidyltransferase determined to 3.0-ångströms resolution | x-ray diffraction | A, B | — | — |
| 1KAN | Molecular structure of kanamycin nucleotidyltransferase determined to 3.0-ångströms resolution | x-ray diffraction | A, B | — | — |
| 1KNY | Kanamycin nucleotidyltransferase | x-ray diffraction | A, B | — | — |
| 1KNY | Kanamycin nucleotidyltransferase | x-ray diffraction | A, B | — | — |
| 6NLT | Apo structure of the T130K mutant of ANT-4 | x-ray diffraction | A, B | CA | 3 (best 0.79) |
| 6NLT | Apo structure of the T130K mutant of ant-4 | x-ray diffraction | A, B | CA | — |
| 6UN8 | Wild type ANT bound to neomycin | x-ray diffraction | A, B | NMY, MG | 3 (best 0.79) |
| 6UN8 | Wild type ant bound to neomycin | x-ray diffraction | A, B | NMY, MG | 3 (best 0.79) |
| P05057 | AlphaFold monomer V2.0 prediction for kanamycin nucleotidyltransferase (P05057) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1KNY chain A against the predicted model P05057: TM-score 0.98, RMSD 0.87 Å
- 1KNY chain A against the predicted model P05057: TM-score 0.98, RMSD 0.87 Å
- 6UN8 chain A against the predicted model P05057: TM-score 0.98, RMSD 0.85 Å
- 6UN8 chain A against the predicted model P05057: TM-score 0.98, RMSD 0.85 Å
- 6NLT chain B against the predicted model P05057: TM-score 0.98, RMSD 0.86 Å
- 6NLT chain B against the predicted model P05057: TM-score 0.98, RMSD 0.86 Å
- 6UN8 chain B against the predicted model P05057: TM-score 0.98, RMSD 0.88 Å
- 6UN8 chain B against the predicted model P05057: TM-score 0.98, RMSD 0.88 Å
- 6NLT chain A against the predicted model P05057: TM-score 0.98, RMSD 0.91 Å
- 6NLT chain A against the predicted model P05057: TM-score 0.98, RMSD 0.91 Å
Elsewhere
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