UniProt P05023
Sodium/potassium-transporting ATPase subunit alpha-1 (P05023)
Sodium/potassium-transporting ATPase subunit alpha-1 (UniProt P05023), EC 7.2.2.13: 5 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 17 pockets. Binding sites, druggability and experiment against…
- UniProt
- P05023
- Protein
- Sodium/potassium-transporting ATPase subunit alpha-1
- EC
- 7.2.2.13
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 17 · 1 record with a druggable one
Structures
6 records of P05023 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7E1Z | Cryo EM structure of a Na+-bound Na+,K+-ATPase in the E1 state | electron microscopy | A | NA, MG, Y01, PC1 | — |
| 7E1Z | Cryo EM structure of a na+-bound NA+,K+-ATPase in the E1 state | electron microscopy | A | NA, MG, Y01, PC1 | — |
| 7E20 | Cryo EM structure of a K+-bound NA+,K+-ATPase in the E2 state | electron microscopy | A | K, MG, Y01, PC1 | — |
| 7E21 | Cryo EM structure of a Na+-bound Na+,K+-ATPase in the E1 state with ATP-gamma-S | electron microscopy | A | NA, MG, AGS, Y01, PC1 | 17 (best 0.77) |
| 7E21 | Cryo EM structure of a na+-bound NA+,K+-ATPase in the E1 state with ATP-gamma-S | electron microscopy | A | NA, AGS, Y01, PC1 | — |
| P05023 | AlphaFold monomer V2.0 prediction for SODIUM/POTASSIUM-transporting ATPase subunit alpha-1 (P05023) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7E20 chain A against the predicted model P05023: TM-score 0.97, RMSD 2.12 Å
- 7E1Z chain A against the predicted model P05023: TM-score 0.67, RMSD 6.43 Å
- 7E1Z chain A against the predicted model P05023: TM-score 0.67, RMSD 6.43 Å
- 7E21 chain A against the predicted model P05023: TM-score 0.66, RMSD 6.47 Å
- 7E21 chain A against the predicted model P05023: TM-score 0.66, RMSD 6.47 Å
Elsewhere
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