UniProt P04951
3-deoxy-manno-octulosonate cytidylyltransferase (P04951)
3-deoxy-manno-octulosonate cytidylyltransferase (UniProt P04951), EC 2.7.7.38: 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 40 pockets. Binding sites, druggability and experiment against…
- UniProt
- P04951
- Protein
- 3-deoxy-manno-octulosonate cytidylyltransferase
- EC
- 2.7.7.38
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 40 · 3 records with a druggable one
Structures
7 records of P04951 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1VH1 | Crystal structure of CMP-KDO synthetase | x-ray diffraction | A, B, C, D | — | 14 (best 0.74) |
| 1VH1 | Crystal structure of cmp-kdo synthetase | x-ray diffraction | A, B, C, D | — | — |
| 3K8D | Crystal structure of E. coli lipopolysaccharide specific CMP-KDO synthetase in complex with CTP and… | x-ray diffraction | A, B, C, D | MG, KDO, CTP | 14 (best 0.81) |
| 3K8D | Crystal structure of E. COLI lipopolysaccharide specific cmp-kdo synthetase in complex with CTP and… | x-ray diffraction | A, B, C, D | — | — |
| 3K8E | Crystal structure of E. coli lipopolysaccharide specific CMP-KDO synthetase | x-ray diffraction | C, D, A, B | — | 12 (best 0.69) |
| 3K8E | Crystal structure of E. COLI lipopolysaccharide specific cmp-kdo synthetase | x-ray diffraction | C, D, A, B | — | — |
| P04951 | AlphaFold monomer V2.0 prediction for 3-deoxy-manno-octulosonate cytidylyltransferase (P04951) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3K8E chain D against the predicted model P04951: TM-score 0.98, RMSD 0.84 Å
- 3K8E chain D against the predicted model P04951: TM-score 0.98, RMSD 0.84 Å
- 3K8E chain A against the predicted model P04951: TM-score 0.98, RMSD 0.89 Å
- 3K8E chain A against the predicted model P04951: TM-score 0.98, RMSD 0.89 Å
- 3K8E chain C against the predicted model P04951: TM-score 0.98, RMSD 0.86 Å
- 3K8E chain C against the predicted model P04951: TM-score 0.98, RMSD 0.86 Å
- 3K8E chain B against the predicted model P04951: TM-score 0.98, RMSD 0.87 Å
- 3K8E chain B against the predicted model P04951: TM-score 0.98, RMSD 0.87 Å
- 1VH1 chain D against the predicted model P04951: TM-score 0.97, RMSD 1.12 Å
- 1VH1 chain D against the predicted model P04951: TM-score 0.97, RMSD 1.12 Å
Elsewhere
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